Pediatrics and Child Health

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Browsing Pediatrics and Child Health by Author "Abebe,Workeabeba(Prof.)"

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    Prevalence and Outcome of Health- Care Associated Infection in Neonates Admitted to Neonatal Intensive Care Unit Tikur Anbessa Specialized Hospital, Addis Ababa Ethiopia.
    (Addis Ababa University, 2023-11) Sany,Elham; Abebe,Workeabeba(Prof.)
    Background: Health care–associated infections are infections acquired in the hospital while receiving treatment for other conditions. Healthcare-associated infection (HAI) is a serious problem in neonates who are admitted to the neonatal intensive care unit (NICU) because of impaired host-defense mechanisms, limited amounts of protective endogenous flora on skin and mucosal surfaces at time of birth, reduced barrier function of their skin, use of invasive procedures and devices, and frequent exposure to broad spectrum antibiotic agents. Due to variations in definitions and reporting, the exact global burden of HAI cannot be accurately estimated. There exists wide variation in the bacteriological profile and antibiogram of microorganisms in different NICUs which changes consistently with time. Objective: To assess the prevalence and outcome of HAI in neonates. Study Setting: The study will be conducted in NICU of Tikur Anbessa Specialized Hospital, Addis Ababa from December 2023 to January 2023. Method: A hospital based retrospective cross-sectional study will be conducted on prevalence and outcome of HAI in neonates. A data collection sheet will be designed to include baseline and progress data for each admitted neonate who develops HAI. Data collection protocol will be prepared, and data collectors will be trained as per the protocol. After data cleaning and entry, analysis will be done using the Statistical Package for Social Sciences (SPSS). Descriptive and analytical statistics will be used as applicable. Statistically significant association will be taken for p values of <0.05. Work Plan and Budget: This study will be conducted from December 2023 to January 2024. This period will be utilized to finalize the research proposal, collect, and analyze the data. A total of 40,000 birr will be used to cover the costs for data collection and supplies
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    Quality of life and associated factors among caregivers of children with Down syndrome aged 6-month to 18 years and associated factors in Tikur Anbessa Specialized Hospital, Ethiopia
    (Addis Ababa University, 2024-03) G/meskel,Martha; Abebe,Workeabeba(Prof.)
    Down syndrome (DS), also known as trisomy 21, is the most common chromosomal disease in humans and is caused by an extra copy of chromosome 21. Given that children with DS frequently have significant morbidities, this can place an immense burden on their caregivers and negatively affect their quality of life (QoL). Even though there are a sizable number of children with DS in our setup, there are no studies that specifically address the burden that having a child with DS puts on these caregivers. Objectives: aim to assess the Quality of caregivers and associated factor among caregivers of children with DS. Method: A cross-sectional study design was used to assess different variables of QoL among caregivers of children with DS at TASH. Data was collected using the WHOQoL-BREF tool through a modified face-to-face interview, and chart reviews for a calculated sample size of 292. Mean and SD were used to present continuous variables. Frequency and percentage are used to present categorical variables. The analysis will be done using SPSS Version 28, ANOVA, independent sample t-test, and Kruskal-Wallis test were used to compare continuous variables among different groups. Multiple linear regression analysis was used to determine factors independently associated with different domains. Result Among the 285 included caregivers, the mean age was 37.8±7.99. Over half of caregivers were between 30-39 years old 155, (54.4%). The WHOQoL-BREF score findings in this study revealed that the mean scores for physical health and psychological domain were 53.43 and 58.05, respectively, which are relatively higher compared to the lower mean scores for Social relationship and Environmental domains which are 45.71 ±22.44 and 43.39 respectively. Caregiver education status, sex, household income and perceived severity of child illness showed significant association with the four domain of quality of life (P-value <0.05). Conclusion and recommendation:-This study revealed that caregivers of children with Down syndrome have a significantly compromised quality of life in all the 4 domains of QoL, particularly in social relations and environmental health domains. Poor economic condition, sex of caregiver, lower education level and perceived severity of their children’s illness are significant determinants of their QoL. This is indicative of the need for a coordinated care plan for children with down syndrome and their caregivers and we suggest further qualitative and case controlled studies to better define the kind of intervention these study group urgently requires.