Prevalence of transfusion transmissible infections, ABO blood grouping and antibody screening among blood donors at Defense Health Main Department Bella Blood Bank Center of Addis Ababa, Ethiopia.

dc.contributor.advisorTsegaye, AsterMSc, PhD)
dc.contributor.advisorAlemu, Jemal(MSc, PhD Candidate)
dc.contributor.advisorTamir, Zemenu(MSc, PhD Candidate )
dc.contributor.authorBelay, Benyam
dc.date.accessioned2020-05-21T13:21:24Z
dc.date.accessioned2023-11-06T08:56:30Z
dc.date.available2020-05-21T13:21:24Z
dc.date.available2023-11-06T08:56:30Z
dc.date.issued2019-06
dc.description.abstractBackground: The presence of blood borne infections in blood cells or plasma of asymptomatic donors is the major risk factors for transmitting infectious agents through blood transfusion.Common infectious agents include Hepatitis B virus,Hepatitis C virus , Human immunodeficiency virus and Syphilis . Objective: To determine prevalence of transfusion transmissible infections ,ABO blood grouping and Antibody screening among blood donors at Defense Health Main Department Bella Blood Bank center of Addis Ababa, Ethiopia. Methodology: A retrospective study on the magnitude of TTIs among blood donors was conducted from January2010 to April2019 at Defense Health Main Department Bella Blood Bank center Addis Ababa, Ethiopia. The socio-demography, TTI, ABO typing and antibody screen data was first entered into Excel spread sheet from the institutions file by removing any identifier, cleaned and then finally exported to SPSS Version24 software for analysis.Proportion and P-value was used to calculate statistical significances. P-value<0.05 was considered as statistically significant. Result: The overall prevalence of TTI was 99(10.8%) out of 927 voluntary donors. The prevalence is 93(11.8%)in male and 6(4.2%) in Female. Majority affected agegroup were 46-58(16.4%) followed by 36-45(10.4).The prevalence of HIV,HBV, HCV and Syphilis was 8(0.9%),46(5%),23(2.5%)and 22(2.4%) respectively.Five out of 927(0.53%)had multiple infections, the most common combinations were HBV-HCV 2(0.21%), HBV-Syphilis 2(0.21%) and Syphilis-HCV 1(0.1%). Antibody screening profile revealed 1(0.1%)positive. Conclusion: Th e overall prevalence of TTI was 10.8. promoting of health education among the donor community and enhancement of voluntary donation is recommended.en_US
dc.identifier.urihttp://etd.aau.edu.et/handle/123456789/21269
dc.language.isoen_USen_US
dc.publisherAddis Abeba Universityen_US
dc.subjectTTI, ABO,Antibodyscreen,voluntary blood donors.en_US
dc.titlePrevalence of transfusion transmissible infections, ABO blood grouping and antibody screening among blood donors at Defense Health Main Department Bella Blood Bank Center of Addis Ababa, Ethiopia.en_US
dc.typeThesisen_US

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