Prevalence of transfusion transmissible infections, ABO blood grouping and antibody screening among blood donors at Defense Health Main Department Bella Blood Bank Center of Addis Ababa, Ethiopia.
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Date
2019-06
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Addis Abeba University
Abstract
Background: The presence of blood borne infections in blood cells or plasma of
asymptomatic donors is the major risk factors for transmitting infectious agents through
blood transfusion.Common infectious agents include Hepatitis B virus,Hepatitis C virus ,
Human immunodeficiency virus and Syphilis .
Objective: To determine prevalence of transfusion transmissible infections ,ABO blood
grouping and Antibody screening among blood donors at Defense Health Main
Department Bella Blood Bank center of Addis Ababa, Ethiopia.
Methodology: A retrospective study on the magnitude of TTIs among blood donors was
conducted from January2010 to April2019 at Defense Health Main Department Bella
Blood Bank center Addis Ababa, Ethiopia. The socio-demography, TTI, ABO typing and
antibody screen data was first entered into Excel spread sheet from the institutions file by
removing any identifier, cleaned and then finally exported to SPSS Version24 software
for analysis.Proportion and P-value was used to calculate statistical significances.
P-value<0.05 was considered as statistically significant.
Result: The overall prevalence of TTI was 99(10.8%) out of 927 voluntary donors.
The prevalence is 93(11.8%)in male and 6(4.2%) in Female. Majority affected agegroup
were 46-58(16.4%) followed by 36-45(10.4).The prevalence of HIV,HBV, HCV and
Syphilis was 8(0.9%),46(5%),23(2.5%)and 22(2.4%) respectively.Five out of 927(0.53%)had multiple infections, the most common combinations were HBV-HCV 2(0.21%),
HBV-Syphilis 2(0.21%) and Syphilis-HCV 1(0.1%). Antibody screening profile revealed
1(0.1%)positive.
Conclusion: Th e overall prevalence of TTI was 10.8. promoting of health education
among the donor community and enhancement of voluntary donation is recommended.
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Keywords
TTI, ABO,Antibodyscreen,voluntary blood donors.