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Analysis of Concurrent Chemoradiation Dosimetryin Nasopharyngeal Cancer at Black Lion Hospital: A1-Year Retrospective Study
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Date
2024-12-13
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Addis Ababa University
Abstract
This study aimed to analyze the dosimetric parameters in NPC patients
specifically on target dose coverage, conformity index (CI), homogeneity index (HI), OAR
sparing, and adherence to international target volume coverage guidelines and protocols.
Methods: A retrospective institution-based observational court study conducted dosimetric
analysis for 50 NPC patients treated with RT from June 2023 to June 2024. Dosimetric
parameters were analyzed for each PTV at 70Gy, 59,4Gy, and 54Gy. Conformity index (CI)
and homogeneity index (HI) were calculated to evaluate target coverage and OAR sparing.
Dose-volume histograms form treatment planning software (TPS) were analyzed and
compared with published tolerance doses in the literature. One-tailed Wilcoxon Signed Rank
test was performed to compare dosimetric findings with guideline recommendations
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Keywords
Concurrent Chemoradiation Dosimetryin Nasopharyngeal