Profiling and Antimicrobial Susceptibility Pattern of Non-Fermentative Gram- Negative Bacilli Isolated from Patients Referred to Arsho Medical Laboratory Addis Ababa, Ethiopia.
| dc.contributor.advisor | Bitew, Adane(MSc, Ph.D.) | |
| dc.contributor.author | Tatek, Mihiret | |
| dc.date.accessioned | 2021-12-12T09:26:21Z | |
| dc.date.accessioned | 2023-11-06T08:57:01Z | |
| dc.date.available | 2021-12-12T09:26:21Z | |
| dc.date.available | 2023-11-06T08:57:01Z | |
| dc.date.issued | 2021-09 | |
| dc.description.abstract | Background: Non-Fermenting Gram-Negative Bacilli are defined as strictly aerobic and nonspore forming group of bacteria. They are intrinsically resistant to many antibiotics. Globally the burden of multidrug resistance in Gram-negative bacilli represents a daily issue for the management of antimicrobial therapy in patients. Objective: The aim of this study was profiling and antimicrobial susceptible pattern of nonfermentative Gram- negative bacilli isolated from patients referred to Arsho Advanced Medical laboratory Addis Ababa, Ethiopia. Methods: A cross sectional study were conducted in Arsho advanced medical laboratory Addis Ababa, Ethiopia from January 2020 to August 2021 on 705 clinical samples. From this, isolates were detected from different clinical samples such as urine, body fluid, blood, CSF and other samples which was collected from patients. All the samples received in the microbiology laboratory were inoculated on blood agar, MacConkey agar and chocolate agar and incubated at 37°C for 48hr. Non fermentative Gram-negative bacilli was isolated and identified from clinical specimens by standard procedure and antibiotic sensitivity test was performed by VITEC 2. Gram reaction of the organisms was determined by Gram stain. Results: From the total of 705 various specimens, 137 (34.5%) were culture positive for Nonfermentative Gram-negative bacteria, Among the isolated bacteria, the highest number was Acinetobacter baumannii 26/137(3.7%). While Pseudomonas aeruginosa accounts 20/137 (2.8) followed by Proteus mirabilis 16/137 (2.3%). Among NFGNB P. aeruginosa (100%), and A. baumanii (100%) were multi drug resistance. Conclusion: Antimicrobial resistance and multi drug resistance was performed during the study period was high, it is due to ordering antibiotic without knowing the right pathogen and also unlimited use of antibiotics. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/29208 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Abeba University | en_US |
| dc.subject | Non-fermentative, Gram- negative bacilli, antimicrobial susceptible, antimicrobial resistantAddisAbaba,Ethiopia. | en_US |
| dc.title | Profiling and Antimicrobial Susceptibility Pattern of Non-Fermentative Gram- Negative Bacilli Isolated from Patients Referred to Arsho Medical Laboratory Addis Ababa, Ethiopia. | en_US |
| dc.type | Thesis | en_US |