Prevalence of Hepatitis B Virus, Human immune Deficiency Virus and Associated Risk Factors among Individuals with Presumptive Pulmonary Tuberculosis Attending at St. Peter`s Specialized Hospital, Addis Ababa, Ethiopia.
| dc.contributor.advisor | Nigatu, Wondatir (MSc, PhD) | |
| dc.contributor.advisor | Desta, Kassu ( MSc, PhD Candidate) | |
| dc.contributor.advisor | G/heir, Atsbaha (MSC, PhD Candidate) | |
| dc.contributor.author | G/hiwet, Kahasit | |
| dc.date.accessioned | 2020-12-13T06:18:46Z | |
| dc.date.accessioned | 2023-11-06T08:56:41Z | |
| dc.date.available | 2020-12-13T06:18:46Z | |
| dc.date.available | 2023-11-06T08:56:41Z | |
| dc.date.issued | 2020-06 | |
| dc.description.abstract | Back ground: Hepatitis B virus (HBV), Human immunodeficiency virus (HIV) & M.Tuberculosis are the causes of widely spread infectious disease around the world, especially in resource limited countries. On the other hand the magnitude of HBV infection among Pulmonary tuberculosis (PTB) suspected individuals was not well addressed. Objective: To assess the prevalence of HBV, HIV & their associated risk factors and the magnitude of TB among individuals with presumptive pulmonary tuberculosis (PTB) attending at St. Peter`s Specialized hospital, Addis Ababa, Ethiopia. Methods: A cross sectional study was conducted among 387 individuals with presumptive PTB from October to December 2019. A convenient sampling technique was employed. A standard questionnaire was used to collect socio-demographic data & associated risk factors from the study subjects. Sputum & whole blood samples were collected. Sputum samples were analyzed by Gene Xpert, Florescent Microscopy & Zehl Neelson`s staining technique. HBsAg ELISA test was done by Murex Version 3 ELISA test kit from serum/Plasma samples , HIV testing was performed as per the testing algorithm recommended by national guideline and data was analyzed using SPSS version 23. Results:- Of 387 study participants 214 (55.3%) males & 173 (44.7%) females were included in this study. Overall 14 (3.6%), 28 (7.2%) & 37 (9.6%) of the TB suspected were positive for HBV, HIV & TB respectively. HBV- HIV co-infection was found to be 1 (0.3%). The TB -HIV co-infection was identified in 6 (1.6%). There was no HBV-HIV-TB triple infection. In the multivariate analysis having partner separated, Alcohol consumption, body piercing & having multiple sexual partner were significantly associated with HBV infection. Having partner separated, widowed, sharing scissors, alcohol consumption & contact with multiple sexual partner also significantly associated with HIV infection. Conclusion: This study shows that HBV, HIV& TB are still a public health issues which needs awareness and health education on the risky behaviors & transmission of HBV ,HIV &TB among individuals with presumptive TB. Further studies also required. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/23986 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Abeba University | en_US |
| dc.subject | HBV, HIV, Presumptive TB, Gene Xpert , ZN, FM | en_US |
| dc.title | Prevalence of Hepatitis B Virus, Human immune Deficiency Virus and Associated Risk Factors among Individuals with Presumptive Pulmonary Tuberculosis Attending at St. Peter`s Specialized Hospital, Addis Ababa, Ethiopia. | en_US |
| dc.type | Thesis | en_US |