Assessment of Magnitude and Associated Risk Factors of Post Operative Nausea and Vomiting After Elective Surgury Under General Anesthesia At Tikur Anbesa Specialized Hospital Addis Ababa, Ethiopia, 2018.
| dc.contributor.advisor | Melese Eyayalem | |
| dc.contributor.author | Tolosa Chali | |
| dc.date.accessioned | 2018-11-02T06:36:34Z | |
| dc.date.accessioned | 2023-11-05T09:40:03Z | |
| dc.date.available | 2018-11-02T06:36:34Z | |
| dc.date.available | 2023-11-05T09:40:03Z | |
| dc.date.issued | 2018-05 | |
| dc.description.abstract | may increase patient’s morbidity. Nowadays, it has become a common phenomenon with the increasing number of surgeries. Various pharmacological and non-pharmacological methods had been employed to control postoperative shivering. Warming the patient and other alternativemethods has been employed over several years, but it was more expensive. Objectives: to compare the effectiveness of intravenous ketamine 0.5mg/kg and pethidine 0.5mg/kg for post-operative shivering after general anesthesia at black lion specialized hospital from January 1 to April 30, 2018. Methods and materials: an observational cohort study was conducted at black lion specialized hospital from January 1 to April 30, 2018. The study involved 76 ASA I and II patients aged 18-65 years, undergoing elective surgery under general anesthesia. The patients in the two groups took either ketamine 0.5mg/kg and pethidine 0.5 mg/kg 20 minutes before completion of the surgery. The incidence and severity of post-operative shivering were compared between the two groups every 10 minutes until one hour postoperatively. Categorical data were analyzed with the Chi-Square test and fisher exact test. Parametric data between groups were analyzed using independent samples t-test and non-parametric data were analyzed with Mann-Whitney U test. Ap value of <0.05 was considered as a statistically significant. Results: The incidence of shivering between the ketamine and pethidine groups in PACU were(28.2%) and (35.9%) respectively (p=0.467). Grades of shivering were not significantly different between the two groups (p=0.893). Comparison of HR and MAP at different time intervals intraoperatively was found to be comparable between the groups (p>0.05). The scores of axillary temperature at different time intervals during intraoperative and postoperative period have shown comparable values. Conclusion and Recommendation: This study showed that prophylactic low dose IV ketamine reduced postoperative shivering as effectively as pethidine. The study also showed a clinically better outcome in favor of ketamine. We recommend prophylactic low dose IV ketamine 20 minutes before completion of surgery to prevent postoperative shivering. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/13635 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | Post-operative nausea, Post-operative vomiting, General anesthesia | en_US |
| dc.title | Assessment of Magnitude and Associated Risk Factors of Post Operative Nausea and Vomiting After Elective Surgury Under General Anesthesia At Tikur Anbesa Specialized Hospital Addis Ababa, Ethiopia, 2018. | en_US |
| dc.type | Thesis | en_US |