Assessment of clinical profile and outcome of patients with acute coronary syndrome in Tikur Anbessa and AaBET Hospitals ,Addis Abeba, Ethiopia.

dc.contributor.advisorDr.Debebe, Finot
dc.contributor.advisorDr.Zewde, Tigist
dc.contributor.authorMebrahtom, Girmawi
dc.date.accessioned2020-04-02T12:24:47Z
dc.date.accessioned2023-11-05T09:38:36Z
dc.date.available2020-04-02T12:24:47Z
dc.date.available2023-11-05T09:38:36Z
dc.date.issued2018-07
dc.description.abstractBackground: Coronary artery disease (CAD) is the leading cause of mortality and morbidity in the world. Although no countrywide study has been done on cardiovascular disease (CVD) in Ethiopia some hospital based studies have shown the incidence of CVD is progressively increasing. Methodology: A retrospective cross sectional study was conducted on the clinical profile of patients with Acute Coronary Syndrome (ACS) In Tikur Anbessa and AaBET hospitals using a structured questionnaire from January 2016 to February 2018. The data were entered, analyzed and interpreted using SPSS version 20 software. Result: Of 142 patients with ACS, 62 (48.6%) were diagnosed as STEMI. The mean age was 57.5±12.09 years. The average time from onset of ACS symptoms to presentation in the emergency department was 2.4 days (61.96 hours) ±48.85. In about 101 (71.1%) patients, hypertension was identified as a risk factor for development of ACS. Nearly fifteen percent (14.8 %) of ACS patients in Tikur Anbessa and AaBET hospitals were either Killip class III or IV. The in-hospital mortality was 9.8%. Predictors of inhospital mortality in Tikur Anbessa and AaBET hospitals included female sex (P=0.016), time from symptom onset to presentation (P=0.04), being Killip class III and IV (P=0.001), and STEMI diagnosis (P=0.018). Conclusion: Patients with ACS have delayed presentation to the hospital from onset of symptoms. Patients had similar risk profiles with the developed world, but have higher mortality. Being female, delayed presentation, having STEMI, and higher Killip class was found to be independent predictors of in hospital mortality in Tikur Anbessa and AaBET Hospitals.en_US
dc.identifier.urihttp://etd.aau.edu.et/handle/123456789/21241
dc.language.isoen_USen_US
dc.publisherAddis Abeba Universityen_US
dc.subjectAcute coronary syndrome, Ethiopia, Emergency departmenten_US
dc.titleAssessment of clinical profile and outcome of patients with acute coronary syndrome in Tikur Anbessa and AaBET Hospitals ,Addis Abeba, Ethiopia.en_US
dc.typeThesisen_US

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