Quality Assessment of Platelet Concentrates Prepared from Different Time Intervals Held Whole Blood at Ethiopian Blood and Tissue Bank Service, Addis Ababa, Ethiopia
| dc.contributor.advisor | Zemenu Tamir | |
| dc.contributor.author | Muluken Kassahun | |
| dc.date.accessioned | 2025-08-12T17:15:13Z | |
| dc.date.available | 2025-08-12T17:15:13Z | |
| dc.date.issued | 2023-07-21 | |
| dc.description.abstract | Background: The objective of this research is to meet the ever-growing demand for blood and blood components in health facilities, especially platelet concentrate, which is extremely high. The short shelf life of platelet concentrate is another reason for the shortage. Therefore, with the need to generate a new additional method to increase the supply of platelet concentrate, this study uses platelet concentrates prepared from whole blood held at different time intervals. In addition, it included almost all quality assurance requirements to ensure its quality. Objective: The purpose of this study was to assess quality of platelet concentrates prepared from different time intervals held whole blood at Ethiopian Blood and Tissue Bank Service, Addis Ababa. Methods: A Cross sectional research was done on 153 samples taken from 25 female and 128 male non-ruminated volunteer blood donors and whose age was range 18 to 61 years at Ethiopian Blood and Tissue Bank Service from August 1 to October 30, 2022. Convenient sampling was used; all whole blood collected at mobile and static centers were included. The selected whole blood was held for 8, 16 and 24 hours at room temperature and processed into its component according to SOPs; then platelet concentrates were assessed for their quality parameters based on the national standards. The data collection was checked before analytical, during analytical and after analytical steps then, data was entered, checked, cleaned, and fed into Microsoft Excel software and then imported into SPSS version 26 for further statistical analysis. Mann-Whitney U test, the Wilcoxon Signed-Rank Test and Friedmanās test were used for pairwise group comparison, within group pairwise comparisons and triple measure within group median comparisons, respectively. P 0.05) Key words: Whole blood; Platelet concentrate; platelet quality | |
| dc.identifier.uri | https://etd.aau.edu.et/handle/123456789/6375 | |
| dc.language.iso | en_US | |
| dc.publisher | Addis Ababa University | |
| dc.subject | Whole blood Platelet concentrate platelet quality | |
| dc.title | Quality Assessment of Platelet Concentrates Prepared from Different Time Intervals Held Whole Blood at Ethiopian Blood and Tissue Bank Service, Addis Ababa, Ethiopia | |
| dc.type | Thesis |