Placenta In Preeclamptic and Gestational Diabetes Mellitus Mothers: A Macroarchitectural Study at Gandhi and Black Lion Hospitals Addis Abeba ,Ethiopia
| dc.contributor.advisor | Tolera, Amenu (PhD) | |
| dc.contributor.author | Wubale, Yibeltal | |
| dc.date.accessioned | 2018-06-13T07:44:06Z | |
| dc.date.accessioned | 2023-11-29T04:16:17Z | |
| dc.date.available | 2018-06-13T07:44:06Z | |
| dc.date.available | 2023-11-29T04:16:17Z | |
| dc.date.issued | 2016-10 | |
| dc.description.abstract | Globally, preeclampsia and gestational diabetes mellitus are known to have an average prevalence of 6% and 4% respectively. Both clinical conditions are thought to impact on morphophysiology of placenta. Placenta is a dual sourceorgan that structurally and functionally connects the developing fetus to the uterine wall during pregnancy. This fetomaternal organallowsuptake of nutrients,elimination of wastes and exchange of gases. Pregnancy is usually complicated by preeclampsia and gestational diabetes mellitus, which in turn will alter the macroarchitecture and functions of the placenta as well as health of the pregnant mothers. Hence, this study was conducted to assess the macroarchitectural changes of placenta in preeclampsia and gestational diabetes mellitus mothers as compared to uncomplicated mothers who gave birth at Gandhi Memorial and Black Lion Specialized Hospitals, Addis Ababa, Ethiopia. It was an observational comparative cross-sectional studycarried outat Gandhi and Black Lion Hospitals, from June, 2016- August, 2016. A total of 125 fresh placentas from uncomplicated, preeclampsia and gestational diabetes mellitus mothers were implemented. Themacroarchitecture of placenta were examined by inspection and measuring. The data were analyzed by independent- samples t-test and chi square. Accordingly, the finding shows that the shapes of placentas were circular in 80% of uncomplicated, 72% of preeclamptic and 76% of gestational diabetes mellitus, while oval in 14% of uncomplicated, 20% of preeclamptic and 8% of gestational diabetes mellitus. In addition, it was irregular in 6% of uncomplicated, 8% of preeclamptic and 16 % of gestational diabetes mellitus. The weight of placenta in uncomplicated, preeclamptic and gestational diabetes mellitus mothers respectively were 499.4, 456.20 and 583.68 gram. The numbers of cotyledon were 18.66 in uncomplicated, 17.24 in preeclamptic and 22.56 in gestational diabetes mellitus mothers. The diameter was19.4, 17.66 and 23.50 centimeter in order of uncomplicated, preeclamptic andgestational diabetes mellitus mothers. The thicknesses were1.96centimeter inuncomplicated, 1.72centimeterin preeclamptic and 2.34 centimeterin gestational diabetes mellitus mothers. According to the present study most of macroarchitecture (diameter, thickness, weight and number of cotyledon) of placenta were significantly decreased in preeclamptic and increased in gestational diabetes mellitus mothers | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/614 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Abeba University | en_US |
| dc.subject | Preeclamptic; Diabetes; Macroarchitectural Study | en_US |
| dc.title | Placenta In Preeclamptic and Gestational Diabetes Mellitus Mothers: A Macroarchitectural Study at Gandhi and Black Lion Hospitals Addis Abeba ,Ethiopia | en_US |
| dc.type | Thesis | en_US |