Onychomycosis: Prevalence and spectrum of fungal etiological agents among patients attending the dermatology clinic at All African Tuberculosis and Leprosy Rehabilitation Training CenterOnychomycosis: Prevalence and spectrum of fungal etiological agents among patients attending the dermatology clinic at All African Tuberculosis and Leprosy Rehabilitation Training Center
| dc.contributor.advisor | Bitew, Adane (Msc, PhD) | |
| dc.contributor.author | Wolde, Sinkinesh | |
| dc.date.accessioned | 2018-11-30T07:52:47Z | |
| dc.date.accessioned | 2023-11-06T08:56:21Z | |
| dc.date.available | 2018-11-30T07:52:47Z | |
| dc.date.available | 2023-11-06T08:56:21Z | |
| dc.date.issued | 2018-07 | |
| dc.description.abstract | Background: Onychomycosis is among the most frequent forms of human infections; being estimated to affect more than 20-25% in worldwide, and their incidence is constantly increasing particularly in developing countries. Although onychomycosis is considered to be a trivial disease the psychological effects of onychomycosis is highly considerable and because of its high morbidity it is a costly disease in terms of loss of working days and treatment. Anyone can get a fungal nail infection. Some people may be more likely than others to get a fungal nail infection, including older adults and people who have nail injury or nail surgery, Diabetes and a weakened immune system and blood circulation problems. Objective: - To determine the prevalence of onychomycosis and profile fungal etiologic agents collected from clinical suspected samples in All African TB and Leprosy Rehabilitation Training Center. Methods: -a cross sectional study design from January to May, 2018 was conducted. A total of 303 study participants were collected by convenient sampling techniques. By using standard structured questionnaire socio-demographic data was collected and fungal pathogen from scraped nail sample was isolate and identified by using KOH microscopic examination and cultivation on sabouroud and chromo agar. Data was analyzed using SPSS version 23 software and P- value < 0.05 was considered as statically significant. Results:-The overall prevalence is of onychomycosis185/303(61.3 %) in our study site. Non Dermatophytes was the most prevalent (34.5%), followed by dermatophytes (28.1%), yeast (25.9%) and mixed (10%). fungal pathogen .Aspergillus was the most common species (spp) isolated among the non dermatophytes, whereas t.tonsurans and t.mentagrophyte spp were among the dermatophytes and from yeast genes Candida albican were isolated. Conclusion: The prevalence and profile of fungal onychomycosis infections seems to be related to age, life style, and the presence of co-morbidities (P= 0.03). The present study indicated that non dermatophytes were the main agents causing onychomycosis. In the meantime performing direct examination and fungal culture was important to diagnoseand treat the patients. Predisposing factors have a contribution to increase the incidence of onychomycosis. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/14743 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | OnychomycosisPrevalence Risk factors | en_US |
| dc.title | Onychomycosis: Prevalence and spectrum of fungal etiological agents among patients attending the dermatology clinic at All African Tuberculosis and Leprosy Rehabilitation Training CenterOnychomycosis: Prevalence and spectrum of fungal etiological agents among patients attending the dermatology clinic at All African Tuberculosis and Leprosy Rehabilitation Training Center | en_US |
| dc.type | Thesis | en_US |