Assessment of gonadal and cortisol hormone profile among drug abusers visited zewditu memorial hospital for the purpose of HIV behavioral and biological surveillance (IBBS) survey, Addis Ababa, Ethiopia
| dc.contributor.advisor | Kinde, Samuel (MSc, PhD fellow) | |
| dc.contributor.author | Yibrah, Messeret | |
| dc.date.accessioned | 2018-12-21T08:29:02Z | |
| dc.date.accessioned | 2023-11-06T08:56:24Z | |
| dc.date.available | 2018-12-21T08:29:02Z | |
| dc.date.available | 2023-11-06T08:56:24Z | |
| dc.date.issued | 2017-01 | |
| dc.description.abstract | Background Drug abuse and its related complications are one of the most important public health problems in a world and it is becoming an increasing problem in Ethiopia.it can lead to social, health, economical and other problems. However, to the best of our knowledge data’s regarding gonadal and cortisol hormone profile of drug abusers are limited, and there is no published data which is similar with our study in Ethiopia in general and the study area in particular. Objective: to assess gonadal and cortisol hormone profile among drug abusers visited Zewditu memorial hospital for the purpose of HIV Behavioral and Biological Surveillance (IBBS) Survey ,Addis Ababa, Ethiopia. Method: A case control study was conducted to assess gonadal and cortisol hormone profile among drug abusers from stored serum sample from March 01-30, 2017.a total of 148 drug abusers and 23 controls using convenience sampling technique was included. Any information regarding the study population was obtained from questionnaire and interview filled previously. Serum level of LH, FSH, T, E2 and Cortisol was assayed. Data was entered and analyzed using SPSS version 20 statistical software and Mann- Whitney test and median was used to compare groups. Percentage and frequency was used to show distribution of descriptive data. In all cases, P-value less than 0.05 were considered as statistically significant. Result: Serum testosterone and LH level were significantly decreased in khat, marijuana and heroin abusers compared to control group. But serum level of estradiol was significantly increased among the khat , marijuana and heroin abusers as compared to control groups. The other hormone parameters [cortisol and FSH] was not statistically significant among khat, marijuana and heroin users compared to control group. Conclusion: In conclusion, our data suggest that gonadal [LH, testosterone and estradiol] hormones are affected as a result of drug use [khat, marijuana and heroin]. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/15222 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | Gonadal hormone, Cortisol hormone, Drug abuse | en_US |
| dc.title | Assessment of gonadal and cortisol hormone profile among drug abusers visited zewditu memorial hospital for the purpose of HIV behavioral and biological surveillance (IBBS) survey, Addis Ababa, Ethiopia | en_US |
| dc.type | Thesis | en_US |