Synthesis, In Vitro Antimicrobial, and In Silico Analysis of Camphor-Based Schiff Base Derivative

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dc.contributor.advisorDaniel Bisrat
dc.contributor.authorTseganesh Abate
dc.date.accessioned2026-06-22T15:50:09Z
dc.date.available2026-06-22T15:50:09Z
dc.date.issued2025-12-10
dc.description.abstractMicrobial diseases are among the leading causes of mortality and morbidity worldwide. The rise of antimicrobial resistance has become a significant challenge, as microorganisms have developed resistance to many existing drugs. Therefore, the search for new antimicrobials is critically important. Schiff bases (SB) and their derivatives exhibit a wide range of biological activities, including antimicrobial, anti-inflammatory, antimalarial, anticancer, and antioxidant effects, among others. Camphor (1) is a terpenoid (1, 7, 7-trimethylbicyclo [2.2.1]-2-heptanone), exists in two enantiomeric forms (1S)-m (-) is a synthetic camphor and (1R)-(+) is a natural camphor.
dc.identifier.urihttps://etd.aau.edu.et/handle/123456789/8406
dc.language.isoen_US
dc.publisherAddis Ababa University
dc.subjectR-camphor
dc.subjectSchiff bases
dc.subjectsynthesis
dc.subjectantimicrobial activity
dc.subjectmolecular docking
dc.subjectADMET
dc.titleSynthesis, In Vitro Antimicrobial, and In Silico Analysis of Camphor-Based Schiff Base Derivative
dc.typeThesis

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