Synthesis, In vitro Antimicrobial and In silico Studies of Sulfonated Derivatives of Carvacrol

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dc.contributor.advisorDaniel Bisrat
dc.contributor.authorAyne Teje
dc.date.accessioned2026-06-22T15:53:34Z
dc.date.available2026-06-22T15:53:34Z
dc.date.issued2025-06-05
dc.description.abstractThe emergence of new pathogens and antimicrobial resistance pose significant challenges in treating infectious diseases. These ongoing challenges necessitate the discovery of new drugs. In medicinal chemistry research, carvacrol has become a focus of research as a lead compound due to its multifaceted pharmacological activities particularly its notable antimicrobial activity. Additionally, numerous studies have highlighted the substantial antibacterial potential of sulfonated compounds including sulfonic acids and sulfonate esters. Consequently, this study aimed to synthesize sulfonate derivatives of carvacrol, assess their in vitro antimicrobial activity against 26 bacterial and 4 fungal strains and conduct an in silico analysis
dc.identifier.urihttps://etd.aau.edu.et/handle/123456789/8448
dc.language.isoen_US
dc.publisherAddis Ababa University
dc.subjectCarvacrol
dc.subjectantimicrobial activity
dc.subjectantimicrobial resistance
dc.subjectantibacterial activity
dc.subjectantifungal activity
dc.subjectsulfonated carvacrol
dc.subjectsynthesis
dc.subjectin vitro
dc.subjectin silico studies
dc.titleSynthesis, In vitro Antimicrobial and In silico Studies of Sulfonated Derivatives of Carvacrol
dc.typeThesis

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