School of Nursing and Midwifery
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Item Assessment of Dialysis Treatment Outcome and Associated factors among Chronic Kidney Disease Patients Attending Selected Governmental Hospitals Dialysis Treatment Center Addis Ababa, Ethiopia.(Addis Ababa University, 2023-01) Mebratie,Simegn; Welde,Mistire(MSc, PhD Ass.Prof.); G/Egziabher,Tatek (MSc, PhD Candidet)Background: Chronic kidney disease is an advanced loss in kidney function over a period of time. It is identified by higher amount of creatinine and lower glomerular filtration rate. Chronic kidney disease is a growing problem worldwide leading to increasing incidence of life- threatening complications and mortalities. Dialysis treatment is an indication of end stage renal disease in the chronic kidney disease patients. Effective dialysis procedure is reducing renal damage and disease complication. Objective: the aim of this study was to assess the effective dialysis treatment and associated factors among chronic kidney disease patients at selected hospital Addis Ababa Ethiopia from April to June 2022. Methods: A Hospital based Cross sectional study was conducted at the three selected hospitals from April to June 2022. Proportion to population size was applied to determine the proportion of participants from the study areas based on the number of chronic kidney disease dialysis patients that attended the hospitals during the study period. During the study, besides to collecting socio-demographic information, history of comorbidity and treatment questionnaires related to risk factor assessment for poor dialysis outcomes were administered. Blood sample were collected and serum creatinine and urea were analyzed and calculated using Cockcroft Gault equation for eGFR. The effectiveness of dialysis was evaluated with URR, Kt/v and eGFR. The collected data was encoded, checked, cleaned and entered in to Microsoft excel software, and then imported to SPSS version 26 software for further statistical analysis. Result: The total study subjects were 102. Of them 65(63.7%) were males and the mean ±SD age of the subject was 38.67 ± 13.06 years with 18-86 years range. The mean ±SD of URR, KT/V and eGFR values were 68.74% ± 20.61, 1.46 ± 0.24 and 25.63± 12.38ml/min/1.73m2 respectively. Assessment of hemodialysis results 64(62.75%) and 75(73.5%) were very good in URR and KT/V respectively. 71(69.6%) were good in eGFR value. Conclusion: The present study indicated that overall evaluation of dialysis treatment conducted at the selected hospitals were very good.Item Assessment of Knowledge and Attitude Towards Cervical Cancer and ScreeningAssessment of Knowledge and Attitude Towards Cervical Cancer and Screening Among Female Students at Menlik Ii Health Science College, Addis Ababa, Ethiopia.(Addis Ababa University, 2015-06) Michael, Haile; Gemechu, Endalew (PhD)Background: Cervical cancer is the second most common cancer among women worldwide. About 83% of the cases occur in developing countries, representing 15% of female cancers .In Ethiopia, prevalent cancer among women between 15 and 44 years of age with age specific incidence rate of 15.6/1000. Carcinoma of the cervix is a preventable disease; its prevention, among other ways, is through screening and detection of premalignant stages of the disease and treatment. Detection of the cervical cancer however requires knowledge of the disease and cervical cancer screening procedure so that people can be aware and positive towards screening but in Ethiopia little has been explored about knowledge and attitude of women towards cervical cancer screening. Objective: To assess knowledge and attitude of Female Students aged >18 years towards Cervical Cancer Screening in Menlik II Health Science College of Addis Ababa, Ethiopia from March 23 to April 30 2015. Methods: A cross-sectional institutional based study was conducted on a sample of 292 Female Students aged >18 years in Menlik II Health Science College of Addis Ababa Ethiopia using simple random sampling method .Data on knowledge status of mothers regrinding cervical cancer screening, attitude of female students towards cervical cancer screening and other pertinent variables were collected using self-administered questionnaires .The gathered data was analysis the software SPSS version 20. Results Generally the knowledge was poor, attitude was positive to majority of respondents. The results showed that 65(22.2%) had poor knowledge, 180(61.4%) had satisfactory knowledge and only 48(16.4%) had good knowledge. Overall 168(57.7%) of the respondents were positive about cervical cancer screening. Conclusions and recommendations: The study has shown that there is a lack of knowledge on cervical cancer towards screening for premalignant cervical lesion. There is a need to promote cervical cancer screening among women by Informing or teach them on their susceptibility to cervical cancer and encouraging a belief that active and regular screening can detect cervical cancer at the pre-cancerous stage, hence enabling them early treatment and prevention of cancer development. There is also a need for provision of Affordable screening services all over the country to enable women, after being motivated, to go for screening. KEY WORDS: Knowledge, attitude, Female, Students, Addis Ababa, EthiopiaItem Assessment of Nurses Knowledge Practice and Associated Factors Towards Pediatrics Palliative Care of Nurses Working at Selected Hospitals in Addis Ababa, Ethiopia(Addis Ababa University, 2014-06) Mandesh, Alemnesh; Gebre Kidan, Birhane (Assistant Professor)To provide quality pediatric palliative care at the end of life or with life threatening illness, nurse must have good knowledge and practice about pediatric palliative care . Palliative care is approach that improves the quality of life for children and their families facing the problem. Palliative care is new and specialized field for nurses, very little is known about the type of services offered and the readiness of the nurse to provide palliative care. Knowledge and competences of optimal pain assessment and management at the end – of life enhances nurse’s practical knowledge. Knowledge of palliative care is essential for nurses, especially in pediatrics’, where palliative care is less common than with adults. Objectives: Assessment of nurses’ knowledge practice and associated factors towards pediatrics palliative care of nurses working at selected Hospitals in Addis Ababa, Ethiopia. Material and methods: A cross sectional quantitative study design was carried out on 252 nurses working in selected hospitals of Addis Ababa. For qualitative study FGD was conducted in three groups, one group contains 6-8members. The study was conducted from November to June 2014. Five governmental and two nongovernmental hospitals was selected. These hospitals selected because they admit children of different age for care and treatment. Palliative Care Quiz for Nursing (PCQN) and practical questions tools from African palliative care Association /palliative outcome scale for Africa was used. EPI-INFO and SPSS soft ware statistical package were applied for data entry and analysis .P-value less than 0.05 were considered as statistically significant Result: The response rate was 252 (98.8%) of the total 249 respondents. Out of total study participants only 37(14.8%) had good knowledge toward pediatric palliative care. Bachelor and Master level of education were significantly associated with knowledge of pediatric palliative care. Training on palliative was significantly associated with knowledge of nurses towards palliative care. Concerning their knowledge aspect practice more than half 243(97.5 %) of the respondent had poor knowledge aspect of practice towards pediatric palliative care and 190(76.3%) initiate pediatric palliative care discussion to the family during diagnosis.148(59.4%), inform to the family their child’s terminal stage illness. Age, sex year of working experience pediatric ward had significant association with knowledge aspect practice of pediatric palliative care. Conclusion and Recommendation The finding of this study show nurses participated in this study had poor knowledge (85.2 %) and knowledge aspect practice (97.5%) had poor towards pediatric palliative care. Therefore pediatric palliative should be integrated in to the national health policy and incorporate in nursing curriculum .Training should also be delivered in this field to nurses in hospital. Key words: Addis Ababa, knowledge, nurse, palliative care, pediatrics and practItem Magnitude of Helicobacter Pylori infection among patients with Esophageal cancer and apparently healthy individuals, at Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia; a comparative cross-sectional study.(Addis Ababa University, 2023-06) Eshetu,Yismu; Desta,Kassu(MSc, PhD candidate); Tsegaye,Aster(MSc, PhD); Abera,Dessie(BSc, MSc,); Nega,Birhanu (MD,Prof.); Mamo,Siyasebwe (MD)Background: Helicobacter pylori are Gram-negative bacterium that can cause diverse types of gastrointestinal tract malignancies including esophageal cancer (EC), though evidences regarding EC are conflicting. This study aimed to determine the magnitude of H. pylori among EC as compared to Healthy individuals. Objective: To investigate the magnitude of Helicobacter Pylori infection among patients with esophageal cancer as compared to apparently healthy individuals. Methods: a health facility-based comparative investigation was done from May 2021 to August 2022 cross-sectionally at Tikur Anbesa Specialized Hospital. Convenient sampling was used to recruit 302 (112 cases and 190 (healthy individuals) participants. Cases of EC were clinically confirmed as well as by Histological Examination. Apparently healthy individuals (staff and attendant) were taken as a comparative group. H. pylori stool antigen as well as serum antibody were measured following standard methods. Data analysis was done using SPSS Version 22. Odds ratio was calculated with 95% confidence interval to describe the association between H. pylori and esophageal cancer with level of significance set at p<0.05. Results: Out of 302 study participants, 52% (157/302) were males and 91.1% (102) were residing outside Addis Ababa. Majority, 74.1 % of EC cases had squamous type tumor and 37.4% were in stage II. The magnitude of H. pylori among Esophageal Cancer Patient were 40.2% (45/112) and 4.2% (8/190) in Healthy individuals. H. pylori infection is more infecting the esophageal adenocarcinoma (EAC) type 48.3% (14/29) compared to ESCC which is 37.4% (31/83); highest prevalence was noted in Stage IV patients (57.1 %). In the multivariable logistic regression analysis, being in the age group 40 years and above (AOR=12.23, 95%CI=4.09- 36.53), living outside Addis Ababa (AOR=18.57, 95%CI=5.76-59.8), attaining primary level education and below (AOR=17.24, 95%CI=5.31-55.96), and being positive for H. pylori stool antigen (AOR=20.13, 95%CI=4.79- 84.62) were significantly associated with EC after controlling for throat illness, taking alcohol, family history of throat illness and consuming hot food. Conclusion; Magnitude of Helicobacter pylori was remarkably high among Esophageal Cancer patients compared to Healthy individuals. Further study is needed and moreover, advocacy of patients on the beneficiary effect of identified factors is one strategy to prevent EC.