Internal Medicine

Permanent URI for this collection

http://etd.aau.edu.et/handle/123456789/70

Browse

Browsing Internal Medicine by Subject "COVID -19, Patients"

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    Patterns of Anticoaulation and Outcome in COVID -19 Patients Admitted to TASH Isolation center, Addis Ababa Ethiopia, Retrospective Study (June 2020-June 2021)
    (Addis Ababa University, 2021-12) Nurlegn, Serkalem; Yusuf, Hanan(MD, Assistant Professor and Consultant in pulmonology and intensive care, consultant internist)
    Background Earlier reports of high prevalence of thrombosis and related mortality has led to use of anticoagulants being part of the main treatment with varying results. Despite current large scale data showing credible benefits there are no studies done to determine the pattern of anticoagulation use and outcome in COVID patients in Ethiopia. OBJECTIVE To assess patterns of anticoagulation and outcome, of COVID-19 patients admitted to TASH isolation ward June2020- June 2021. METHODOLOGY Facility based retrospective cross-sectional study using secondary data analysis, was conducted. Records were retrieved using TASH, isolation log book. 126 patients were included. Data was analyzed using descriptive and binary logistic regression analysis Result Of the total 126 cases, Anticoagulation was used in 94 pts 74.6%. Therapeutic dose anticoagulation was used in 13(13.8%) pts of which 8 had severe disease. Prophylactic dose 79(84%), intermediate dose in two pts. UFH was used in 78(82.9%), LMWH 13(13.8%), DOAC 2(2.2%). only 58.8% of the patients received the full dose of prescribed anticoagulation. Pulmonary Thrombo-Embolism occurred in 9 pts of which 8 had severe disease and nearly half were on anticoagulation. Venous thrombosis occurred in 7 pts among those 5 had severe disease. Three out of the seven pts were on anticoagulation. In Hospital mortality was (n=14, 11.8%). Conclusion In conclusion, majority of patients received anticoagulation with UFH in prophylactic dosage. Anticoagulation use was not associated with diseases severity, in hospital mortality or 3 months outcome. Complications of anticoagulation were rare and minor. Complications were not associated with poor outcome.