Browsing by Author "Mammo Wendimagegn"
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Item Attempts Towards the Synthesis of Substituted Pyrrolines(Addis Ababa Universty, 1982-06) Mammo Wendimagegn; Dagne Ermias (PhD)In this project, the reactions of several functionalized compounds possessing the nicotine skeleton have been investigated. Studies also have been conducted on the cycloaddition reactions of C-pyridyl-h-methylnitrone with three olefinic compounds namely, allyl chloride, allyl bromide and allyl alcohol. Plausible mechanisms have been suggested for the formation of nicotine and nicotyrine by the reduction of 5-methoxycotinine and related compounds with lithium aluminum hydride. In the course of this work four new compounds, namelp 4-hydroxynicotine, 4-chloronicotine, 4-hydro: