Oncology

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Browsing Oncology by Author "Argaw Zeleke"

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    Assessment of Nurses Knowledge and Associated Factors Towards Prevention and Management of Cytotoxic Extravasation in Selected Public Hospitals Oncology Units Addis Ababa, Ethiopia, 2021.
    (Addis Ababa University, 2021-06) Adugna Girma; Argaw Zeleke; Berhane Emebet
    Background: Cytotoxic extravasation is the major adverse effect than the combinations of sepsis, neutropenia, mucositis and gastrointestinal disorders. Pain, immobility, irreversible damage of nerve, tissues and tendon, skin grafting and loss of extremity are the significant morbidities secondary to extravasation. Objective: The aim of this study was to assess nurse’s knowledge and associated factors towards prevention and management of cytotoxic extravasation in selected public hospitals, Addis Ababa, Ethiopia, 2021. Methods: A descriptive cross-sectional study design was conducted at Tikur Anbessa Specialized Hospital and Saint Paul Hospital Millennium Medical College that was selected purposely. A convenient sampling technique was employed for the selection of study participants. The data was collected by using a structured self-administered questionnaire. The data entry and cleaning was done by using Epi-data version 4.6 and SPSS version 25. Logistic regression analysis technique was employed to evaluate the effect of independent variables on the dependent variable. Statistical significance was declared with the p
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    Awareness of Colorectal Cancer and its Associated Factors among Adult Patients Attending Jimma University Medical Center South-West, Ethiopia, 2020.
    (Addis Ababa University, 2020-06) Hamza Abdulmenan; Argaw Zeleke ; Gela Debela
    Background: Colorectal cancer (CRC) is the first commonest diagnosed cancer in men and the fourth commonest in women in Ethiopia. The most significant factors that may increase the risk of having CRC were modifiable. These factors were prevented by increasing awareness of the population. Objective: This study aimed to assess the awareness of CRC and its associated factors among adult patients attending Jimma University Medical Center, South-West Ethiopia, 2020. Methods: The institution-based quantitative cross-sectional study design was conducted among 422 patients at Jimma University Medical Center from March 8 to April 30, 2020. The study participants were recruited by a systematic random sampling method and data was collected semi-structured interviewer-administered questionnaires. The collected data were entered into Epi data version 4.6.0 and transferred to SPSS version 25. Descriptive, Bivariate and multivariate logistic regression were implemented. The strength of association was determined by using AOR, 95% CI. The statistical level of significance was stated at P<0.05. Result: A 100% response rate in this study was recorded. More than half (57.6%) of the study participants had low awareness of CRC. The first common and least common risk factors that were known by participants were smoking (78.2%) and aging (32.5%) whereas the most common and least common symptoms were blood in the stool (49.3%) and abdomen lump (33.9%). There is significant association between awareness of colorectal cancer and gender [AOR=1.86; 95% CI (1.26, 2.75)], residency [AOR= 0.45; 95% CI (0.30, 0.67)], monthly income [AOR=4.72; 95% CI (3.11, 7.15)], level of education [AOR=2.83; 95% CI (1.49, 5.37)], information sources [AOR=2.51; 95% CI (1.18,5.37)], and heard about CRC [AOR=4.48; 95%CI (2.90,6.93)]. Conclusion and recommendation: Results showed that awareness of patients towards CRC was inadequate. However, the majority of patients had better awareness of colorectal cancer risk factors. Similarly, participants with high levels of education and females had better awareness of CRC than the reverse. Therefore, there is a need for campaigns and educational programs, from health care authorities, a higher educational institution for the general public and patients.
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    Survival Status and Prognostic Factors among Breast Cancer Women at Selected Hospitals in Southern Ethiopia, 2023.
    (Addis Ababa University, 2023) Desta Bitsiet; Argaw Zeleke
    Introduction: Breast cancer is the major cause of morbidity and mortality worldwide,particularly in countries with limited resources. Patients in developing countries,particularly Ethiopia, are less likely to survive due to delayed diagnosis and advanced-stage presentations. Several studies have been conducted on the prognostic factors amongbreast cancer patients in Ethiopia, but they cannot consider neutrophils to lymphocytes as the prognostic factor. Objective: To assess the survival status and prognostic factors among Breast Cancer womenat selected hospitals in southern Ethiopia,2023. Methods: A retrospective cohort studywas conducted among 507 randomly selected breast cancer women in selected hospitals in southern Ethiopia.Two trained BSc nurses collected the data using an open data kit(ODK).Descriptive statistics were summarized using tables and graphs. The bivariable and multivariable Weibull regression modelswereused to identify the prognostic factors. The final model fitness was investigated using theCox-Snail residual test, and the Schoenfeld residuals test was used to examine theproportional hazards assumption. Results:The overall survival of breast cancer women at the end of two and three years was 54.5% and 23.9%, respectively. An excellent and good Nottingham prognostic score(AHR: 0.26, 95% CI: 0.12, 0.53) and (AHR: 0.39, 95% CI: 0.18, 0.81), chemotherapy(AHR: 0.59, 95% CI: 0.36, 40.93), metastasis (AHR: 1.89, 95% CI: 1.31, 2.74), advancedstages (AHR: 1.73, 95% CI: 1.19, 2.51), hormone therapy (AHR: 0.64, 95% CI: 0.44,0.92), and lower neutrophil to lymphocyte ratio (AHR: 0.68; 95% CI: 0.47; 0.97) were the prognostic factors of breast cancer women. Conclusion: This study revealed that the breast cancer survivorship rate was lower than that of an earlier study from Ethiopia. An increased ratio of neutrophils to lymphocytes at the time of diagnosis and a poor NPI were linked to a worse chance of survival for breast cancer women; this indicated that promoting early diagnosis of breast cancer and treatment could be important to improve the survival of breast cancer patients