College of Health Sciences

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Browsing College of Health Sciences by Author "Ababu Eden"

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    H.Pylori Infection and its Association With Cd4 T Cell Count Among Hiv Infected Individuals who Attended the art Service in Kotebe Health Center, Yeka Subcity, Addis Ababa, Ethiopia
    (Addis Ababa University, 2017-06) Ababu Eden; Desta Kassu
    Background: H.pylori is a gram-negative bacterium found on the luminal surface of the gastricepithelium. At least 50% of the world's human population has H.pylori infection. Studies haveshown an increased prevalence of this bacteria in people infected with HIV relied on the CD4count level.Aim:To determine the burden H.pylori and its association with CD4 count among HIV infectedindividuals who attend the ART service in Kotebe Health Center, Yeka Sub City, Addis Ababa,Ethiopia. Methods:A cross sectional Study was conducted from October to November 2016 on 388HIVinfected individuals at Kotebe Heath Center, Yeka Sub City Addis Ababa. Convenientsampling technique was employed to include study participants who met the inclusion criteria.CD4 count and hemoglobin level with demographic and other variables such as habit ofdrinking alcohol, habit of eating chat, habit of personal hygienic practice, and also direct stoolmicroscopy examination was included in the study. Results:The prevalence of H.pylori infection among study subject was 54.8%, H.pyloriinfection among female participant was 51.8% (133/256) and among male participant was60.6% (87/143) with X2 = 2.745a and P-Value 0.098. The prevalence of H.pylori infection inpatient with CD4 count level less than 500 was 54.4% (131/141) and with CD4 count levelgreater than 500 was 55.1% (81/147).The prevalence of H.pylori was 67.1% (61/91) amongHIV clients with people in the house hold greater than four. The prevalence of H.pyloriinfection among HIV clients those use tanker water, wheel water, pipe water was 50% (2/4),25% (4/16) and 55.9% (226/401) respectively (X2= 6.114a P. value=0.047). Conclusion: There was no significant association between the prevalence of H.pylori and levelof CD4 cell count. But there was significant association between number people in the house hold and type of water used for drinking. And there was no significant association betweenwith socio demographic data like age, sex, marital status, educational level, stage of ARTtaking, habit for drinking of alcohol, smoking, eating of chat, and habit of hand washing, andpervious history of GIT. The health facility and other responsible body must be conscious increating awareness on the possible transmission of the disease. Key words: H.pylori stool antigen test, CD4 cells, HIV, ART