H.Pylori Infection and its Association With Cd4 T Cell Count Among Hiv Infected Individuals who Attended the art Service in Kotebe Health Center, Yeka Subcity, Addis Ababa, Ethiopia
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Date
2017-06
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Addis Ababa University
Abstract
Background: H.pylori is a gram-negative bacterium found on the luminal surface of the gastric
epithelium. At least 50% of the world's human population has H.pylori infection. Studies have
shown an increased prevalence of this bacteria in people infected with HIV relied on the CD4
count level.
Aim:To determine the burden H.pylori and its association with CD4 count among HIV infected
individuals who attend the ART service in Kotebe Health Center, Yeka Sub City, Addis Ababa,
Ethiopia.
Methods:A cross sectional Study was conducted from October to November 2016 on 388HIV
infected individuals at Kotebe Heath Center, Yeka Sub City Addis Ababa. Convenient
sampling technique was employed to include study participants who met the inclusion criteria.
CD4 count and hemoglobin level with demographic and other variables such as habit of
drinking alcohol, habit of eating chat, habit of personal hygienic practice, and also direct stool
microscopy examination was included in the study.
Results:The prevalence of H.pylori infection among study subject was 54.8%, H.pylori
infection among female participant was 51.8% (133/256) and among male participant was
60.6% (87/143) with X2 = 2.745a and P-Value 0.098. The prevalence of H.pylori infection in
patient with CD4 count level less than 500 was 54.4% (131/141) and with CD4 count level
greater than 500 was 55.1% (81/147).The prevalence of H.pylori was 67.1% (61/91) among
HIV clients with people in the house hold greater than four. The prevalence of H.pylori
infection among HIV clients those use tanker water, wheel water, pipe water was 50% (2/4),
25% (4/16) and 55.9% (226/401) respectively (X2= 6.114a P. value=0.047).
Conclusion: There was no significant association between the prevalence of H.pylori and level
of CD4 cell count. But there was significant association between number people in the house
hold and type of water used for drinking. And there was no significant association between
with socio demographic data like age, sex, marital status, educational level, stage of ART
taking, habit for drinking of alcohol, smoking, eating of chat, and habit of hand washing, and
pervious history of GIT. The health facility and other responsible body must be conscious in
creating awareness on the possible transmission of the disease.
Key words: H.pylori stool antigen test, CD4 cells, HIV, ART
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Keywords
H.pylori stool antigen test, CD4 cells, HIV, ART