College of Health Sciences

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Browsing College of Health Sciences by Author ":MeronYohanne"

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    Nasal Colonization of Metacillin-Resistant Staphylococus Aurus Among Surgical Ward Admitted Patients in Asella Referral and Teaching Hospital
    (Addis Ababa University, 2025-03-07) Chaltu Assefa; :MeronYohanne; :Andinet Bekele
    Background: Methicillin Resistant Staphylococcus Aureus (MRSA) Colonization Occurs When the Bacteria Are Present on the Skin Without Causing Symptoms, An Immune Response, Or Noticeable E Cellular Damage. How Ever, Colonization Increases the Risk of Developing an Infection and Serves as a Significant Source of Person-To-Person Transmission On. MRSA Can Be Acquired Through Direct Contact with an Infected Sharing Persona Items with Someone Carrying the Bacteria or Touching Contaminated Surfaces or Objects. Objectives: To Determine the Nasal Colonization Rate of Methicillin-Resistant Staphylococcus Aureus Among Patients Admitted to Surgical Ward at Assela Referral and Teaching Hospital Methods: A Hospital Based Cross Sectional Study Design Was Conducted from June, To November2024.Atotalof283Nasalswabswerecollectedduringadmissionandat Discharge Time and Processed Using Mannitol Salt Agar and Blood Agar. Disk Diffusion Method Was Used for Antimicrobial Susceptibility Testing. Association Of Risk Factors with Colonization of S. Aureus MRSA Was Assessed Using Bivariate and Multivariate with Colonization Logistic Regression. Apvaluelessthan0. 05wastakenasstatisticallysignifi Can’t. All Data Entry and Statistical Analysis Were Done Using Statistical Package for Social Sciences (SPSS) Version 26 Software. Results: Preval Enceofs.Aureusandmrsainthisstudywere16.3% (46/283) And7.1% (20/283) Respectively. Rateofmrsaamongs.Aureuswas43.4% (20/46). We Have Further Evaluated Whether the Isolated Strain Have Persistently Area, Fromatotalof283patients, Only Colonized the Nasal Area, From A Total Of 283 Patients Only 5patient Have Persistent MRSA. In This Study None of The MRSA Isolates Were Sensitive to Penicillin. However, Low Resistance Was Observed for Sulfamethoxazol Trimethoprim and Erythromycin. Conclusion: This Study Showed Lower Rate of MRSA Colonization Among Surgical Ward Admitted Patients Compared to Other Study Conducted in Ethiopia. Resistant To Other Tested Antibiotic Including Ethiopia. Clindamycin Is Also Reported. Therefore, Routine Screening and Infection Preventive Practice Are Crucial in Reducing MRSA Colonization and Its Association Risk.