Assessment of Laryngeal Mask Airway Insertion Conditions, With Co-Administration of Thiopentone, Fentanyl and Halothane
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Date
2015-07
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Addis Abeba University
Abstract
Background: The laryngeal mask airway (LMA) provides a useful alternative for airway
management during spontaneous or controlled ventilation. Because of benefits like, less
hemodynamic changes, minimal increase in intraocular pressure after insertion; and a
lower incidence of sore throat in adults, the use of LMA as an alternative to tracheal
intubation is gaining popularity. So choosing an induction agent that better suppresses the
airway reflexes, at usual induction dose, while, inserting LMA remains important.
Objectives: To assess conditons of LMA insertion by the co-administration of
Thiopentone, Fentanyl and Halothane in elective patients, scheduled for surgery at Tikur
Anbessa Referral Hospital from March16- May 30, 2015.
Methodology: -The study was conducted in TikurAnbessa Referral Hospital March16 - May
30, 2015.The study population was all elective patients, who was scheduled for elective
surgery and for whom intubation with laryngeal mask airway was indicated. Institution
based cross-sectional study was conducted. The total sample size is 42. Data was
collected by observing the patients intubated with LMA under Thiopentone, Fentanyl and
Halothane. Data was analyzed by using SPSS version 16. Association factors were
checked by using cross-tabulation and chi-square.
Results: - Total number of patients involved in this research was 42. Only patients with
ASA classification of class I & II and Mallampati class I &II are involved. The mean age
of the patients involved in the research was 18.13 ± 12.26. The mean weight was 41.92 ±
17.78. Concerning the responses of the patients to LMA insertion, 95.2% of the patients
have adequate jaw relaxation. 41(97.6%) did not develop laryngeal spasm. In 92.7% of
cases LMA was inserted during the first trial. Gagging did not occur in 90.5% of the
cases. Coughing did not occur in 95.2% of the cases. . No movement is recorded in most
of the cases (95.2%). There was no statistically significant change in the MAP and HR of
the patients immediately, 5 minute and 10 minute after LMA insertion. Most of the
patients (45.2%) start spontaneous breathing within the first 10sec after the combination
of the drugs was administered.
Conclusion: - Thiopentone 5.12mg/kg, fentanyl 1.2mcg/kg and halothane 3% mask
ventilated with 100% oxygen for 2.7 min is effective for the insertion of LMA in elective
patients.
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Keywords
Thiopentone; Fentanyl; Halothane