Phytochemical Investigation of the Stem Bark of Securida Longipedunculata

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Date

2024-08

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Addis Ababa University

Abstract

Plants traditionally used in Ethiopian medicine for various ailments including venereal diseases, stomachache, dislocated jaw, headaches, skin cancer, skin infections, contraceptive purposes. Securidaca longipedunculata is an important plant species with potential benefits in the treatment of various ailments. In this study, two compounds were obtained (SLM-1 and SLM-2) from the stem bark of Securidaca longipedunculata by using solvent extraction and column isolation. The solvents were ethyl acetate, cyclohexane, methanol, and chloroform. The compounds that were obtained from stem bark of Securidaca longipedunculata SLM-1 is a group of galotannins, which were 1,5-anhydro-D-glucitol and SLM-2 is ketone group which were 2,3-dimethoxy-4-hydroxy benzophenone .From this, 1,5-Anhydro-D-glucitol was the major one, which accounts for 3.46%; on the other hand, 2,3-dimethoxy-4-hydroxy benzophenone accounts for a for a small amount, which was (0.027%) from the plant material. The isolated compounds were characterized by the spectroscopic techniques, which are 1H NMR, 13C NMR, DEPT-135, HMBC and HSQC.

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Keywords

Phytochemical Investigation, Stem Bark, Securida Longipedunculata

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