EPIDEMIOLOGICAL INVESTIGATION OF MIDDLE EAST RESPIRATORY SYNDROME CORONA VIRUS (MERS-CoV) AMONG DROMEDARY CAMELS IN SELECTED AREAS OF AFAR AND OROMIA REGION, ETHIOPIA
| dc.contributor.advisor | Dr. Fufa Abunna, Dr. Gelagay Ayelet | |
| dc.contributor.author | Getnet, Fekadu | |
| dc.date.accessioned | 2020-06-26T10:11:59Z | |
| dc.date.accessioned | 2023-11-08T11:36:55Z | |
| dc.date.available | 2020-06-26T10:11:59Z | |
| dc.date.available | 2023-11-08T11:36:55Z | |
| dc.date.issued | 2015-06 | |
| dc.description | MSc Thesis | en_US |
| dc.description.abstract | A cross-sectional study was conducted from November 2014 to May 2015 to determine the seroprevalence, assess the presence of active cases through isolation and identify possible risk factors for the MERS-CoV in camels in selected areas of Oromia and Afar regional state of Ethiopia. A total of 472 Dromedary Camel sera were collected and screened with two serological tests: (Pseudoparticle neutralization for screening and Microneutralization test for confirmation. The overall prevalence of MERS-CoV in the study area was (91.5%) (n=432/472). Higher prevalence (92.9%) was recorded in Female Dromedary camel when compared to Male (88.8%) result of multivariate logistic regression shows female camels (OR=2.408) in the study area are 2.4 times at risk of MERS-CoV than male dromedary camel. From Zones included in the study Borena zone recorded the least prevalence (82.2%) (n= 60/73).Multivariate logistic regression shows camels living in Borena zone (OR=0.055) were relatively protected from MERS-CoV when compared to zone 4 of Afar .From the kebeles included camels living in Galifage (OR= 0.018) of Ayssaita district were relatively protected when compared to Urmaytu kebele. Out of 100 swabs collected from four districts (Yabelo, Fentale, Amibara and Dubti) and undergo Real Time PCR , 7 of them evident circulation of MERS-CoV in the study area. Generally this study showed the existence of high seroprevalence of MERS-CoV among Ethiopian dromedary camels and also confirmed with RT-PCR, therefore further study is required to determine its significance from both animal and public health perspectives. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/21865 | |
| dc.language.iso | en | en_US |
| dc.subject | Dromedary Camel | en_US |
| dc.subject | MERS-CoV | en_US |
| dc.subject | Prevalence | en_US |
| dc.subject | Sera, Swab, RT-PCR | en_US |
| dc.subject | Ethiopia | en_US |
| dc.title | EPIDEMIOLOGICAL INVESTIGATION OF MIDDLE EAST RESPIRATORY SYNDROME CORONA VIRUS (MERS-CoV) AMONG DROMEDARY CAMELS IN SELECTED AREAS OF AFAR AND OROMIA REGION, ETHIOPIA | en_US |
| dc.type | Thesis | en_US |