Prevalence of Burkholderia Pseudomallei and other bacterial and other bacterial pathogens in community acquired infections in Tikur Anbessa Specialized hospital and felege hiwot Hospital
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Date
2018-11
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Addis Ababa University
Abstract
Backgroun- Burkholderia pseudomallei (B. pseudomallei) is a causative agent of a severe and fatal infectious disease which is called melioidosis. B. pseudomallei, a Gram-negative bacterium, is an environmental saprophyte found in wet soils. Melioidosis predominantly affects people in regular contact with soil and pooled surface water. The commonest routes of B. pseudomallei infection are thought to be inoculation, inhalation and ingestion.The disease mostly infects adults with an underlying predisposing condition, mainly diabetes mellitus.
Objective;-the objective of the current study was to assess the profile and susceptibility pattern of B. pseudomallei and other pathogenic bacteria from collected clinical specimens of community-acquired infections
Method:-A Hospital based cross sectional prospective study was conducted to determine bacterial profile and antimicrobial susceptibility pattern of pathogenic bacteria from selected clinical specimen from March 2016-June2018in Tikur Anbessa specialized Hospital and Felege Hiwot Hospital in Bahir Dar. During the study period, 315 clinical specimens (either blood, pus, sputum, or urine) from 315 patients were prospectively collected and subjected to microbiological culturing and identification steps.
Result:- Of all the 315 clinical samples collected and subjected to microbiological culturing and identification steps only one isolet (1/315) from pus sample found to be B. Pseudomallei, the rest of the clinical speciment were negative for B. Pseudomallei characterization. However, around 14 other bacterial strains were isolated from those biological samples. Among the 14 other bacterial isolates 42.6% of them were gram positive and the rest 57.4% isoates were gram positive with predominant isolate 39% of S. aureus.
Conclusion:- The current study indicated that the prevalence of bacterial pathogens in the study areas are substancial. Moreover, even if only one isolate of the target organism (B. Pseudominalei) is reported from pus sample of a 20 years old farmer, but it is for the first time in Ethiopia.
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B. pseudomallei, melioidosis, Community acquired infection