Assessment of Renal Function and Hematological Profile among Khat (Catha Edulis) Chewer and non Chewer Type 2 Diabetes Mellitus Patients Attending Harar Jugol Hospital, Eastern Ethiopia.
| dc.contributor.advisor | Degef Maria | |
| dc.contributor.advisor | Addisu Sisay | |
| dc.contributor.author | Reshid Tewekel | |
| dc.date.accessioned | 2021-06-06T06:17:36Z | |
| dc.date.accessioned | 2023-11-29T04:18:24Z | |
| dc.date.available | 2021-06-06T06:17:36Z | |
| dc.date.available | 2023-11-29T04:18:24Z | |
| dc.date.issued | 2021-02 | |
| dc.description.abstract | Background: Diabetes mellitus (DM) is a common endocrine disorder characterized by the presence of chronic hyperglycemia and it’s the leading causeof end stage renal disease (ESRD). In addition to DM some factors suspected tobe the cause of the renal problems are drug abuse. World Health Organization(WHO) classified khat (Catha edulis) as a substance of abuse. Khat interfereswith normal body functions, which could lead to adverse health effects on organs and systems of the body. Objective: The aim of this study was to compare fasting blood sugar (FBS), renalfunction and hematological profile among khat chewer and non chewer type 2DM (T2DM) patients attending at Harar Jugol Hospital, Eastern Ethiopia. Methodology: Comparative cross sectional study was conducted on a total of 100T2DM patients that are divided into two groups (khat chewers and non chewers).Socio demographic data were collected by using standardized questionnaire.Blood sample collection was done through standardized techniques. AutomatedCOBAS 6000 and Sysmex KX-21N hematology analyzers were used to analyzethe samples. Statistical data analysis was held by SPSS version 25 model. Result: Serum FBS and creatinine concentration showed statistically non significant elevation among kaht chewers (p > 0.05). White blood cell (WBC), Platelet (PLT) and hematocrit (HCT) of the khat chewers were significantly higher than non chewers (p<0.05). On the other hand Mean Corpuscular Hemoglobin Concentration (MCHC) and Mean Platelet Volume (MPV) of the khat chewers were significantly lower than non chewers (p<0.05). Conclusion: Chewing khat among T2DM patients might have an effect on FBS, kidney function and hematological profile. Therefore further study is recommended on the effect of khat chewing among DM patients. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/26692 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Abeba University | en_US |
| dc.subject | Khat, Catha edulis, Diabetes mellitus, Renal function, Hematology | en_US |
| dc.title | Assessment of Renal Function and Hematological Profile among Khat (Catha Edulis) Chewer and non Chewer Type 2 Diabetes Mellitus Patients Attending Harar Jugol Hospital, Eastern Ethiopia. | en_US |
| dc.type | Thesis | en_US |