Assessment of Medication Related Problems and Contributing Factors among Ambulatory Patient with Chronic Kidney Disease at St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia
| dc.contributor.advisor | Nedi, Teshome (PhD) | |
| dc.contributor.advisor | Hamza, Leja(MD, Consultant Internist and Nephrologist) | |
| dc.contributor.advisor | Sada, Oumer (Mphar) | |
| dc.contributor.author | Shiferaw, Eshetu | |
| dc.date.accessioned | 2020-11-22T07:32:24Z | |
| dc.date.accessioned | 2023-11-29T04:30:30Z | |
| dc.date.available | 2020-11-22T07:32:24Z | |
| dc.date.available | 2023-11-29T04:30:30Z | |
| dc.date.issued | 2020-06 | |
| dc.description.abstract | Chronic kidney disease (CKD)is the reduction in the Glomerular Filtration Rate (GFR) and urinary abnormalities or a structural abnormality of renal tract which is explained by pathologic kidney abnormalities, persistent proteinuria, and other urine abnormalities on two occasions separated by >90 days. As kidney function declines, number and complexity of medication increase with the progression of the disease. Due to this Patients with this disease are at high risk for medication-related problems because of their condition and the multiple medications required for treatment of the causative disorders, and the complications associated with the disease. This study aimed at establishing the extent of medication related problems among patients with chronic kidney disease as well as exploring associations of different covariates with the problem identified. Hospital based cross-sectional study was conducted among ambulatory patients with chronic kidney disease at St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia from 1 of June to 30 th of August 2019. Patient with chronic kidney disease stage 1, 2, 3, and 4 adult ambulatory patients were included in the study. A total of 325 medication related problems were identified from 204 (82.3%) study participants giving 1.6 MRPs per participants. One medication related problem was identified in 114 (55.9%) patients while two in 64 (31.4%). From the total of identified problems most common class of MRP identified were need additional drug therapy problems 114 (35.1%) followed by non-compliance 54 (16.6%). This study showed that only occupation (AOR=5.2, 95% CI: 1.292-21.288, P=0.020) and Angiotensin converting enzyme inhibitor (ACEI)use (AOR=6.6, 95% CI: 2.202-19.634, P=0.001)had association with the occurrence of medication related problems. In general, our study suggest that medication related problems experienced by each chronic kidney disease patients were high. In terms of types of MRPs, this study showed that need additional drug therapy was frequently identified types. st | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/23439 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Abeba University | en_US |
| dc.subject | Chronic Kidney Disease, Medication Related Problems. | en_US |
| dc.title | Assessment of Medication Related Problems and Contributing Factors among Ambulatory Patient with Chronic Kidney Disease at St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia | en_US |
| dc.type | Thesis | en_US |