Assessment of serum lipid profiles and electrolytes among type II diabetic patients with and without hypertension attending Wolaita Sodo University comprehensive specialized Hospital, Wolaita, South Ethiopia.
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Date
2024-01
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Addis Ababa University
Abstract
Background: Diabetes is disease characterized by hyperglycemia with a disturbance of
metabolism ofcarbohydrates, lipids and electrolytes. Coexistence of high blood pressure,
dyslipidemia and electrolytes disturbance with diabetes has a risk for increased morbidity and
mortality. Despite these alarming figures, data on the biochemical impact of coexisting diabetes
and hypertension — specifically lipid profile and electrolyte variations — are limited in the
Ethiopian population and study area.
Objective: To assess and compare serum lipid profiles and electrolytes level among type II
diabetic patients with and without hypertension attending wolaita sodo university comprehensive
specialized hospital, wolaita, South Ethiopia, from January 2024 to March 2024.
Methods: Hospital based comparative cross-sectional study was conducted on 66 hypertensive
diabetic and 66 normotensive diabetic patients. Trained data collectors gathered the data using a
structured questionnaire. Serum lipid profiles (HDL, LDL, TG and TC) and electrolytes (Sodium,
Potassium and Chloride) were measured by Dimension EXL-200 analyzer. During analysis, Chisquare
is used to compare the study groups by mean level. Binary logistic regression was used to
determine associated factors with lipid profiles and electrolytes abnormality.
Results: The Mean level of TC, TG, LDL, Potassium and Chloride were significantly higher in
HDM as compared with NDM. While, level of HDL-C and Sodium had a significantly lower in
HDM as compared to HDM. In binary logistic regression: Hypertension, BMI, WC and DM
showed strong significant association with abnormal serum level of TG, TC, LDL-C, HDL-C
and Sodium in HDM than NDM.
Conclusion and Recommendation: HDM have more chances to develop high dyslipidemia and
electrolytes disturbance than NDM. Hypertension, BMI, WC and DDM were factors
significantly associated with abnormal lipid profiles and electrolytes level among HDM than
NDM. There should be regular monitoring of lipid profile, electrolytes and hypertension for
diabetic patients to prevent diabetes related complications.
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Keywords
Diabetes Mellitus, Hypertension, Electrolytes, Lipid profiles, WSUCSH