Serum Immunoglobulin Levels in Healthy Ethiopian School Children
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Date
1982-06
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Addis Ababa University
Abstract
Serum conc ent r ations of immunoglobulins 19G, 19A and 19M in
258 healthy Et hiopian school children and 82 healthy adults residing
in Addis Abeba were measured by the r adial immunodi ffusion
t ec hnique . The r esults a r e presented as geometric mean values
in mg/100 ml and as percent of the adult mean val ues. A statis- •
tical analysis showed that the 19G a nd 19A concent r a tions at
ages 8 and 7 r espectively were lower than the adult values . The
infe renc e drawn from these r esults is that the 19G and 19A l evels
do not r each the adult l e vel until a fter the age of 8 and 7
r espective l y . In c ontras t the 19M l evel was found to reach t he
adult l e v e l before the age of 7 . No truly significant differences
we r e observed in immunoglobulin l evels which could be attributed
to se x , intestinal pa rasitic infection or socio-economic status .
The mean values for IgG and 19M obtained from this study were
found to be higher than the r e ferenc e values being used in the
country a t the mome nt. I t is thus suggested that mean immunoglobulin
conc entration val ues obtained from this s tudy be used
as r e f e r ence values until furth e r study is made and more r e fined
r e f e rence value s ar e set .
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Keywords
Healthy Ethiopian School Children