Survival Time of HIV-Infected Children Under 15 Years of Age after Initiation of Antiretroviral Therapy: A Case Study in Bahir Dar

dc.contributor.advisorWencheko, Eshetu(Professer)
dc.contributor.authorAtnafu, Habtamu
dc.date.accessioned2018-06-26T07:52:21Z
dc.date.accessioned2023-11-09T14:29:52Z
dc.date.available2018-06-26T07:52:21Z
dc.date.available2023-11-09T14:29:52Z
dc.date.issued2011-11
dc.description.abstractEven though the use of Antiretroviral treatment has made a marked influence on the survival time of HIV-infected children, all children who received ART drugs do not have the desired level of immune reconstitution. The objective of this study is to assess the survival time of HIVinfected children after ART initiation and to identify factors other than ART that influence the survival time of HIV-infected children who continuously followed ART at Felege-Hiwot Hospital in Bahir Dar. In this study survival data analysis is used to assess survival length of 255 HIV-infected children who followed ART at Felege-Hiwot Hospital in Bahir Dar from 2006 to 2009 for 30 months. To compare the survival time of different groups of children defined by a factor, Kaplan-Meier survival function and the Log-Rank test are used. Cox proportional hazards model is used to model the relationship between significant explanatory variables and survival time. Of the 255 children in the study 71(27.84%) died during the study period. The overall estimated mean survival time of children was 22.381 months with standard error 0.693. Age group, Hemoglobin group and WHO clinical stage of HIV- infected children have been found to be significant factors that affect survival time of children. Therefore, special attention should be given to younger children in ART, children should start ART treatment when they have higher hemoglobin values and children should begin treatment when they are at a lower clinical stageen_US
dc.identifier.urihttp://10.90.10.223:4000/handle/123456789/3573
dc.language.isoenen_US
dc.publisherAddis Abeba universityen_US
dc.subjectHIV-Infected Children Under 15 Years of Ageen_US
dc.titleSurvival Time of HIV-Infected Children Under 15 Years of Age after Initiation of Antiretroviral Therapy: A Case Study in Bahir Daren_US
dc.typeThesisen_US

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