Correlation of angina symptoms, baseline electrocardiogram abnormalities and findings on stress protocol with myocardial perfusion scintigraphy outcomes, a retrospective study, in Monadi Hospital, Naples, Italy.
| dc.contributor.advisor | Guteta,Senbeta(Ass.Prof.) | |
| dc.contributor.advisor | Abeje,Desalegn (MSc) | |
| dc.contributor.advisor | Raddi,Marco(MD) | |
| dc.contributor.author | Shewangizaw,Yonas | |
| dc.date.accessioned | 2024-11-28T09:51:03Z | |
| dc.date.available | 2024-11-28T09:51:03Z | |
| dc.date.issued | 2023-02 | |
| dc.description.abstract | Background: Myocardial perfusion scintigraphy is an imaging modality used in the management of coronary artery diseases. Previous studies have shown that the combination of angina symptoms, baseline electrocardiogram abnormalities, and findings on stress protocols can provide valuable information for predicting the likelihood of abnormal imaging findings. However, the correlation and effect between these variables and imaging outcome is not well established. Objective: To evaluate the correlation and effect between angina symptoms, baseline electrocardiogram abnormalities in coronary artery diseases and during stress exam with abnormal MPS outcomes and their predictive value. Method: Hospital-based single-center retrospective cross-sectional study was conducted using medical records of 328 patients that underwent myocardial perfusion scintigraphy between 2020 and 2022. A systematic random sampling method was used to attain an appropriate sample size. Data were extracted from an electronic database using a checklist. The collected data were coded, entered, and analyzed using SPSS version 26. Pearson chi-square test and logistic regression were performed to evaluate the association and effect of independent variables. The statistical significance was measured at 95% CI and P-value less than 0.05(95%). Results: The study population consisted of 328 patients, among them 185(56.4%) were males and 143(43.6%) were females. A significant association was observed between the severity of the chest pain category, baseline electrocardiogram abnormalities, inducible ischemia, and metabolic equivalent score with abnormal myocardial scintigraphy parameters. For each outcome variable, the aforementioned factors exhibited a statistically significant effect upon logistic regression. The odds of abnormal myocardial perfusion scintigraphy parameters were significantly higher for each independent variable. Conclusions and recommendation: According to results in this study, clinical and electrocardiogram features can help prognosticate coronary artery disease before imaging which can lead to more effective and personalized diagnostic and treatment strategies for patients. Further studies with different methodologies are needed to validate the findings of this study. | |
| dc.identifier.uri | https://etd.aau.edu.et/handle/123456789/3711 | |
| dc.language.iso | en_US | |
| dc.publisher | Addis Ababa University | |
| dc.subject | Myocardial perfusion scintigraphy | |
| dc.subject | Perfusion defect | |
| dc.subject | Metabolic equivalent score | |
| dc.subject | inducible ischemia | |
| dc.title | Correlation of angina symptoms, baseline electrocardiogram abnormalities and findings on stress protocol with myocardial perfusion scintigraphy outcomes, a retrospective study, in Monadi Hospital, Naples, Italy. | |
| dc.type | Thesis |