A retrospective cohort study on the surgical treatment outcome of patients operated for Parasagittal/falcine Meningioma at Tikur Anbessa Specialized Hospital and Myungsung Christian Medical Center from August 1, 2015 to July 31, 2019
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Date
2020-10
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Addis Abeba University
Abstract
Background: The surgical management of parasagittal and falcine meningiomas is challenging
due to their proximity to the superior sagittal sinus and cortical draining veins. This nature of the
tumors poses several hazards of complication related to surgery. There is a limitation of analyzed
and published data on this topic in low-income countries with limited-resource settings.
Objective: This study aims to assess the surgical treatment outcome of parasagittal and Falcine
meningiomas at TASH and MCM, Addis Ababa, Ethiopia.
Methods: This is a hospital-based retrospective cohort study of surgically treated Parasagittal
and Falcine meningioma patients from August 1, 2015, to July 31, 2019. Data was collected
using a well-designed questionnaire, encoded, and analyzed in SPSS version 26. Pearson’s chisquare
and bivariate analysis were done to identify strongly associated factors with the
complications and functional outcome of patients.
Result: A total of 61 patients were operated of which 36(59%) were females. The mean age was
46.1(20 to 78) years. The mean duration of preoperative symptoms was 16.38 (1 to 60) months.
Common preoperative clinical findings were headache in 47(77%) patients, motor weakness in
33(54%) patients, seizure in 26(42.6%), and Visual deficit in 17(27.9%) patients. Mean tumor
size was 5.9(3.5 to 8) cms. Complete resection (SG I or II) was done in 47(77%) patients and
macroscopic GTR(SG I, II, or III) was done in 54(88.5%) patients. Meningothelial was the
commonest histologic type in 29(49.2%) and most tumors were WHO G1 in 47(79.9%) patients.
There were 46 perioperative complications in 17(27.9%) patients. At the end of follow up
53(86.9%) patients were alive and most (45, 84.9%) of the surviving patients had substantial
improvement in functional performance status.
Conclusion: This study showed most of the surviving patients had significant improvement in
their functional performance status which was positively related to the degree of tumor resection
and a better preoperative functional status of the patients. There is a high rate of perioperative
complications and this is strongly related to a longer duration of preoperative symptoms before
their first surgery and the intraoperative incidents.
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Keywords
Parasagittal , Falcine Meningiomas