Assessment Magnitude And Associated Factors OfPediatrics Seizures, At Pediatrics Emergency Unit, Tikur Anbessa Specialized Hospital, Addis Ababa,Ethiopia, 2020
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Date
2020-01
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Addis Abeba University
Abstract
background: - seizure is a transient occurrence of signs and symptoms resulting from abnormal
excessive neuronal activity in the brain. It is an important cause for hospital admissions in children
from developing countries. it accounts for about 1% of all emergency department visits, and about
2% of visits to children's hospital emergency department visits. It is a major factor for neurological
and cognitive impairment in children living in sub-saharan africa. Limited studies have been
conducted in ethiopia relating to the prevalence and associative factors of seizures in children.
Objective: - This study aims to assess the magnitude of seizure and its’ associated factors among 1
month -12 years of age children admitted in tikur anbessa specialized hospital(tash), at the pediatric
emergency unit from december 2016- december 2019.
Result: - Medical records review was done for 256 children with a 96% response rate. The
prevalence of seizure was 4.52 %( 45/1000 people) . 155( 60.5%) were males and with a male to
female ratio of (1.5:1). the mean age of patients was 3.7 years (with standard devation 2.8). The
mean age for onset of a seizure in males and females was 1.3(sd 1.1-1.5 at 95% ci) and 2.0(sd1.6-2.5
at 95% ci) respectively. on logistic regression, fever (or 1.85,p=0.01), newborn distress (or
2.31,p=0.01), hypoxia brain injury (or 2.43,p=0.00), and home delivery (or 2.8,0.04) were found to
be significant predictors seizure.head trauma was 1.3 times more likely to had an earlier onset of the
pediatric seizure, (aor: 1.3,p=0.00) , birth asphyxia, (aor: 2.3,p=0.00) hypoxic brain ischemia, (aor,
2.2,p=0.02)developmental delay, (aor, 2.5,p=0.01),fever, (aor, 1.2,p=0.01),male (aor, 2.7,p=0.01)
were significantly associated with pediatric seizure early onset at p<0.05 with 95% ci.
Conclusion:-:-this study has identified a considerable burden of seizure in younger children in this
hospital. fever, perinatal insults and place of delivery were significantly associated with pediatric
seizure .underlying the need to advocate the need of proper management of pregnancy and delivery
Recommendation; -Health professional at different levels and institution should work to reduce the
occurrence of childbirth asphyxia that commonly show most associations with pediatric seizure.
health facilities better to give health education and health promotion to improve, the awareness on
the risk factors of a seizure.
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Keywords
Seizure, pediatric emergency, tikur anbessa specialized hospital.