Bacterial profiles, antimicrobial susceptibility pattern and associated factors of urinary tract infections among pregnant women attending antenatal care at Tikur Anbesa Specialized Hospital and Lideta Dagim Hidasse Health Center, Addis Ababa, Ethiopia
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Date
2025
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Addis Ababa University
Abstract
BACKGROUND: Urinary tract infection is a common infection affecting any part of the uri-nary system,caused by the invasion and multiplication of microorganisms.Pregnant women are at high risk of developing UTIs due to physiological and anatomical changes.If left un-treated,can lead to complications for both mother and fetus ,making early detection and man-agement essential.
OBJECTIVE: This study was carried out to determine the bacterial profiles, antimicrobial susceptibility pattern and associated factors of urinary tract infection among pregnant women attending antenatal care in Tikur Anbesa Specialized Hospital and Lideta Dagim Hidasse Health Center, Addis Ababa, Ethiopia.
METHODS: A cross sectional study was conducted among 332 pregnant women from April to August 2024 at Tikur Anbesa Specialized Hospital and Lideta Dagim Hidasse Health Cen-ter. A clean-catch midstream urine sample was collected, delivered and inoculated on Mac-Conkey agar and blood agar.Biochemical tests, antimicrobial susceptibility testing and ESBL and carbapenemase production tests were done.All demographic, clinical and laboratory data obtained from the study subjects were entered to SPSS version 20.Logistic regression ,descriptive statistics analyses and odds ratio at 95% confidence interval were carried out to conduct the output of the result.
RESULTS: From the total 332 participants in this study the overall prevalence of urinary tract infection among pregnant women was 30.1%.Among the isolated bacteria gram negative bacteria accounted for 58% while gram positive made up 42%.There was no significance as-sociation between urinary tract infection and socio demographic factors.In clinical diagnosis urine chemical examinationand microscopy was significantly associated with urinary tract infections Also no ESBL and carbapenem resistance gram negative bacteria were found.
CONCLUSION: From this finding we conclude that the prevalence of UTI is high. Any posi-tive cases must be treated to prevent complication during pregnancy.As the study found a significant association between urine chemical examination and microscopy for diagnosing UTIs, regular screening is important for early detection.
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Keywords
Urine tract Infection, Bacterial uropathogens, pregnant women, antimicrobial resistance pattern