Prevalence and Drug Susceptibility Pattern of Bacteria Associated with Urinary Tract Infection Among Hiv Positive Patients Attending Alert Center, Addis Abeba Ethiopia
| dc.contributor.advisor | Ali Ibrahim | |
| dc.contributor.author | Getu Yemisrach | |
| dc.date.accessioned | 2018-07-03T13:51:04Z | |
| dc.date.accessioned | 2023-11-06T08:56:16Z | |
| dc.date.available | 2018-07-03T13:51:04Z | |
| dc.date.available | 2023-11-06T08:56:16Z | |
| dc.date.issued | 2015-06 | |
| dc.description.abstract | Background: Urinary tract infections (UTI) are one of the most common types of bacterial infectionsin humans occurring both in the community and the health care settings. UTI rank high amongst themost common causes that compel an individual to seek medical attention. HIV/AIDS is one of thegreatest public health crisis faced by the global community without a complete cure. UTI represents aconsiderable health problem amongst HIV infected patients. Objective; to determine the prevalence and drug susceptibility pattern of bacteria associated with UTIamong HIV positive patients. Methods: A cross sectional study was conducted in ALERT Center Addis Ababa Ethiopia fromSeptember to January 2015 among 165 adult HIV patients. Midstream urine (MSU) was collectedfrom the study participants with sterile wide mouthed urine cups. Urine samples were inoculated in toBlood agar, MacConkey and Cysteine lactose electrolyte deficient and biochemical tests wereperformed to identify isolates. Drug susceptibility pattern of isolates was determined using the discdiffusion techniques.Data were analyzed using SPSS version-20 software package. Chi – square (X2) test was used tocompare categorical data and to compare associations between proportions. Differences wereconsidered significant when the p-values were < 0.05 at 95% confidences limit. Result: Among the total 165 study participants 114 were females and the remaining 51 were malesand the mean of age was 37.9. The overall prevalence of UTI was 15.7. High bacterial isolates werefound in asymptomatic study participants than symptomatic HIV positive patients. Among Gramnegative isolates Escherichia coli were the leading cause of UTI followed by Gram positive isolatesStaphylococci aureus. Most bacterial isolates were resistant to Amp, TE, P and SXT and Gentamicinwere susceptible for all isolates. Conclusion: the prevalence of UTI was high, and both Gram-negative and Gram positive organismswere causes of UTIs. In this study the chance of acquiring UTI was higher among females than males.UTI prevalence was also high among study participants those have previous history of catheterizationand UTI. E. coli were the most predominant organisms followed by Staphylococci aureus and most ofthe bacterial isolates were sensitive to Gentamicin, Ceftriaxone, Ciprofloxacin, Norfloxacine, Oxacilinand Nitrofurantion. Multi-drug resistance bacteria were common Key words: Asymptomatic UTI, Symptomatic UTI, urinary tract infection, HIV/AIDS, Ethiopia | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/6042 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | Asymptomatic UTI Symptomatic UTI Urinary tract infection HIV/AIDS | en_US |
| dc.title | Prevalence and Drug Susceptibility Pattern of Bacteria Associated with Urinary Tract Infection Among Hiv Positive Patients Attending Alert Center, Addis Abeba Ethiopia | en_US |
| dc.type | Thesis | en_US |