Assesement of Prevalence,Types and Associated Risk Factors of Neutral Tube Defects in Pregnant Women Visiting Health Centers in Addis Abebe.
| dc.contributor.advisor | Zewdineh, Daniel(Associate Professor of Radiology) | |
| dc.contributor.advisor | Gorfu, Yocabel(Assistant Professor of Radiology) | |
| dc.contributor.author | Legesse, Aga | |
| dc.date.accessioned | 2020-02-03T12:03:55Z | |
| dc.date.accessioned | 2023-11-05T09:31:58Z | |
| dc.date.available | 2020-02-03T12:03:55Z | |
| dc.date.available | 2023-11-05T09:31:58Z | |
| dc.date.issued | 2019-09 | |
| dc.description.abstract | Introduction:Central nervous system (CNS) defects are the second most common congenital anomalies after congenital heart diseases. Neural tube defects (NTD’s) are amongst the major CNS defects with significant public health burden and long term morbidity and functional impairment. Central nervous system (CNS) defects are the second most common congenital anomalies after congenital heart diseases. Neural tube defects (NTD’s) are amongst the major CNS defects with significant public health burden and long term morbidity and functional impairment. Many literatures recommend offering screening for NTDs to all pregnant women. Amniotic fluid AFP (AF-AFP) and amniotic fluid acetylcholinesterease (AChE) are the primary biochemical tests performed on amniotic fluid for detection of open neural tube defects. The other modality used for screening of these defects is prenatal ultrasound scan. Method:This hospital based cross sectional prospective study tried to show the utility of ultrasound and the prevalence and pattern of occurrence of these defects.About total of 956 pregnant mothers who came to the hospital were evaluated with ultrasound scan. Results:We found a total of 6 open NTD’s out of this group. There were 2 anencephaly, 1 Chiari II, 1encephalocele and 1 had both anencephaly and spinabifida. Only 55 % if the respondents took IFA supplement during pregnancy and of those who took the supplement 43% took it for a maximum of 1 week. Of the parameters we found TCD has a strong correlation with the calculated mean gestational age. Conclusion and recommendation:The above findings reflect a high incidence of these defects. The low coverage of folic acid supplement as well as poorer socioeconomic factors all would contribute to the observed burden of the disease. Comprehensive screening and preventive strategies must be designed. Further studies and decisions policy maker level are necessary to improve the current figures. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/20545 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | Central nervous system,Neural tube | en_US |
| dc.title | Assesement of Prevalence,Types and Associated Risk Factors of Neutral Tube Defects in Pregnant Women Visiting Health Centers in Addis Abebe. | en_US |
| dc.type | Thesis | en_US |