Umbilical Cord Blood Hematological Parameters Reference Interval for Newborns in Ambo University Referral Hospital, Ambo, Ethiopia.
| dc.contributor.advisor | Tsegaye,Aster(Prof.) | |
| dc.contributor.advisor | Urgesa,Fikadu(MSc, PhD Fellow) | |
| dc.contributor.author | Soboka,Barecha | |
| dc.date.accessioned | 2026-06-22T16:00:08Z | |
| dc.date.available | 2026-06-22T16:00:08Z | |
| dc.date.issued | 2025-04 | |
| dc.description.abstract | Background: Hematology RIs in newborns are a good informative for the evaluation of newborn‘s health condition. The values may possibly indicate difference within some factors such as Birth weight, Sex, and other factors. However, Published information/data on Reference Intervals of hematological parameter of newborns from UBC for Ambo and the surroundings of AURH is lacking. Objective: To determine RIs for umbilical cord blood hematological parameters of newborns In Ambo, Ethiopia. Methods: A cross-sectional study was conducted from April 1 to June 30, 2024GC on Newborns with normal birth weight (2.5-4Kg) by using convenient non-probability sampling technique in Ambo town. About 2-3ml UBC was collected according to standard operating procedure from cord by using EDTA tube. Sample analysis was performed by using Sysmex XN-550. Finally, the data was entered and then data analysis was performed by using the SPSS version 25. Reference Intervals of 2.5th and 97.5th was established by using non parametric method. Result: 200 umbilical cord samples were collected from newborns and out of these 57% were female. Mean ± SD WBC (14.4±5.08), RBC (4.13±0.49), HGB (15.9±2.88), HCT (47.2±8.28), MCV (127.2±9.97), MCH (35.1±1.97), MCHC (40.5±4.17), RDW-CV (14.4±3.60), PLT(207.1±55.29), LYM(37.2±6.96), NEU%(58.3±9.04), MPV (11.2±8.60), PDW-CV (13.6±2.57). RBC counts are similar between sexes, with males at a median of 4.2 and females at 4.18. From our Results of Complete blood count (CBC), HGB and HCT, show no significant. Platelet counts are consistent across genders (P=0.057) whereas WBC indicate no significant sex-related differences. Conclusion and Recommendation: This study highlights the needs for region-specific hematological RIs for umbilical cord blood within newborns from Ambo, due to significant differences from other populations. Broader studies are recommended to improve clinical assessments and public health strategies tailored to local contexts. | |
| dc.identifier.uri | https://etd.aau.edu.et/handle/123456789/8504 | |
| dc.language.iso | en_US | |
| dc.publisher | Addis Ababa University | |
| dc.subject | Complete Blood Count | |
| dc.subject | neonates | |
| dc.subject | hematological RIs | |
| dc.subject | Umbilical cord blood | |
| dc.title | Umbilical Cord Blood Hematological Parameters Reference Interval for Newborns in Ambo University Referral Hospital, Ambo, Ethiopia. | |
| dc.type | Thesis |