Retrospective study of correlation of radiologic diagnosis of mediastinal masses with pathology findings, Tikur anbessa specialized hospital, Addis Ababa University, Addis Ababa, Ethiopia.
| dc.contributor.advisor | Alwan, Amir (MD, Consultant Radiologist) | |
| dc.contributor.author | Dr. Mohammed, Semira | |
| dc.date.accessioned | 2018-10-24T06:18:43Z | |
| dc.date.accessioned | 2023-11-05T09:31:57Z | |
| dc.date.available | 2018-10-24T06:18:43Z | |
| dc.date.available | 2023-11-05T09:31:57Z | |
| dc.date.issued | 2017-10 | |
| dc.description.abstract | Background : Mediastinum is a site of non-neoplastic and neoplastic lesions, many of which present as mediastinal masses. In the study of the imaging appearance, distribution, and other features of various mediastinal masses comparison with the histopathologic diagnosis is important to make an accurate diagnosis. Objective: To assess the imaging pattern of mediastinal masses with pathology correlation. Method: Hospital based retrospective cross sectional study were conducted at Tikur Anbessa Specialized Hospital [TASH]. All patients who had mediastinal mass and having both imaging and pathology result during the period of January, 2015 to May 2017 were included. Fifty patients were included in the study. Data were entered in Epi-Info version 3.5.1 and analyzed by SPSS version 23.0 software of computer. Descriptive statistics was performed. And sensitivity with 95% confidence intervals (CIs) was calculated for each mediastinal mass and for the overall mediastinal mass. Result: Anterior mediastinal masses formed 56.0% of total masses, followed by multiple compartments 22.0% and posterior mediastinum masses 16.0%. Based on CT findings thymic masses formed the majority, 39.3%, of anterior mediastinal masses. Whereas the pathology finding showed thymic masses and lymphoma formed the majority of anterior mediastinal masses constituting 35.71% each. Based on CT and pathology findings the majority, 75.0% and 62.5%, of the posterior mediastinal mass were neurogenic tumors respectively. The sensitivity of CT in detecting neurogenic tumors lymphoma, thymoma and thymic carcinoma were 80%, 68.75%, 60.0% and 80.0% respectively. The overall CT sensitivity for diagnosis of mediastinal masses were appears 76.74% with 95% CI (64.11, 89.37). Conclusion: The most common location of mediastinal mass was anterior mediastinum. Thymic mass and lymphoma are the most common type of mass in anterior mediastinum. Neurogenic tumors were most prevalent tumors of the posterior compartment. Over all computed tomography has 76.74% sensitivity for diagnosing mediastinal masses in TASH. To increase the sensitivity and diagnostic accuracy; there need to be a feedback mechanism from pathology side for each mediastinal mass CT diagnosis. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/13113 | |
| dc.language.iso | en_US | en_US |
| dc.subject | radiology,pathology findings | en_US |
| dc.title | Retrospective study of correlation of radiologic diagnosis of mediastinal masses with pathology findings, Tikur anbessa specialized hospital, Addis Ababa University, Addis Ababa, Ethiopia. | en_US |
| dc.type | Thesis | en_US |