Chemical Composition of Croton Macrostacrys
| dc.contributor.advisor | Abegaz Berhanu (PhD) | |
| dc.contributor.author | emberu, Dirshaye | |
| dc.date.accessioned | 2022-01-24T06:48:29Z | |
| dc.date.accessioned | 2023-11-09T16:19:14Z | |
| dc.date.available | 2022-01-24T06:48:29Z | |
| dc.date.available | 2023-11-09T16:19:14Z | |
| dc.date.issued | 1981 | |
| dc.description.abstract | The root- bark powder of Croton macrostachys Hochstex. A. Rich . (Euphorheaceae) ( n nCj') , used in Ethiopia for curing spreading wounds, was extraced with diethyl ether . The crude extract, on fractionation by column chromatography (Silica gel) yielded a major solid compound A (mp 210- 212o ) crystallizable from acetone- methanol (9 ; l) into be autiful needle aggregates, the structure of which was identified , using I R, PHR and MS data , to be that of lupeol , aknown antitumor agent. The tumor inhibitor y compound Crotepoxide which was previously isolated from the fruits could not be detecte in t he rootbark extract. Preliminary investigation also showed the presence of trace solids B and C having the same Rf on TLC. B was water isoluble white solid while C was water soluble and showed strong blue fluorescence unde r UV- I amp. The presence of quaternary alkaloid was also confirmed in the root- bark . | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/12345678/29561 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa | en_US |
| dc.title | Chemical Composition of Croton Macrostacrys | en_US |
| dc.type | Thesis | en_US |