Viral Load Suppression and Associated Factors among HIV/AIDS Patients on Art in Addis Abeba, Ethiopia, 2021.

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Date

2021-08

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Addis Abeba University

Abstract

Background: HIV continues to have a major impact on public health globally with an estimated 36.9 million people living with HIV (PLHIV) including 1.8 million new infections in 2017.As 2017 national guidelines for comprehensive HIV prevention, care and treatment of Ethiopia, all people living with HIV are eligible for ART irrespective of their CD4 count and clinical stage. Little is known about the viral load suppression of clients who initiate ART irrespective of their CD4 count and clinical stage in Addis Ababa. The aim of this study is to assess the viral load suppression of rapid ART initiation of confirmed HIV positive client’s and factors associated with their outcome. Objectives: To assess the viral load suppression of rapidly initiated ART clients compared with not rapid ART initiated clients and its associated factors at public health facilities of Kirkos s/city, Addis Ababa, Ethiopia in 2021. Methods: A retrospective cohort study was conducted among 356 HIV/AIDS positive patients selected from nine public health facilities of kirkos sub-city in Addis City from July to August /2020. The main exposure variable is Rapid ART initiation and the main outcome variable is the viral load suppression. The data were entered and cleaned using EPI data version 3.1 and analyzed with SPSS version 25. Bivariate and multivariable logistic regression analyses were employed to know the factors that affect the viral load suppression of clients who start ART by their category. Result: This study Clients who start ART rapidly were 4.5 times more likely to have viral load suppression when compared with not rapid ART started clients with p-value 0.008[AOR 4.46 (95% CI= (1.48-13.42)].Clients who have primary education were almost 13 times [AOR = 12.88, (95% CI= 2.90-57.12)] more likely to have viral load suppression compared with clients who do not educated. Clients who have poor drug adherence were less likely to have viral load suppression with p-value of <0.001[AOR 0.00(95% CI=0.00- 0.02)] compared with clients who have good drug adherence. Conclusion: This study shows rapid ART initiation has good viral load suppression than not rapid ART initiation. To get viral load suppression clients adherence to ART is a crucial part.

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HIV/AIDS patients,ART

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