Valuing health-state: an eq-5d-5l value set for Ethiopians
| dc.contributor.advisor | Gedif, Teferi (BPharm,MSc, PhD) | |
| dc.contributor.author | Gebregziabiher, Abraham | |
| dc.date.accessioned | 2018-12-21T11:41:05Z | |
| dc.date.accessioned | 2023-11-06T08:09:56Z | |
| dc.date.available | 2018-12-21T11:41:05Z | |
| dc.date.available | 2023-11-06T08:09:56Z | |
| dc.date.issued | 2018-11 | |
| dc.description.abstract | Background: There is a growing interest in health technology assessment and economic evaluations in developing countries using measures such as EQ-5D-5L (European quality 5 dimension- 5 level). However, the main challenge is lack of local population value sets which are recommended in most countries as they reflect local preferences. Objective: To obtain social preference and establish an EQ-5D-5L value set from the Ethiopian general population. Methods: A sample reflecting urban, and rural population (n= 1,050) was recruited using stratified multi-stage quota sampling technique. Face-to-face, computer-assisted interviews using the EuroQol Portable Valuation Technology (EQ-PVT) software of composite time trade-off(c-TTO) and discrete choice experiments (DCE) were undertaken to elicit preference score. The feasibility of EQ-PVT was pilot tested in a sample of the population (n=110). A hybrid regression model combining c-TTO and DCE data was used to estimate the final value set. Results: The pilot study revealed that the feasibility of EQ-PVT protocol was good and there were no special concerns with undertaking TTO task. The predicted value for the EQ-5D-5L ranged from-0.7186 to 1. The coefficients generated from a hybrid model were logically consistent. Anxiety/depression showed the most impact to utility decrement of 0.4578, and self-care influenced the least 0.2224. The maximum predicted value beyond full health was 0.9741 for the ‘11112’ (health state of slight problem in anxiety/depression dimension). Conclusions: This study established Ethiopian value set for EQ-5D-5L on the basis of c-TTO and DCE. It is expected to facilitate health economic evaluations, health-related quality of life research and to inform decision making in Ethiopia. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/15263 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | Discrete choice experiment, EQ-5D-5L, Ethiopia, Health state valuation, Quality of life, Time trade-off, Utility. | en_US |
| dc.title | Valuing health-state: an eq-5d-5l value set for Ethiopians | en_US |
| dc.type | Thesis | en_US |