Compare the Effectiveness of prophylactic intravenous ketamine 0.5mg/kg and pethidine 0.5mg/kg for postoperative shivering in patients undergoing elective surgery under general anesthesia at Tikur Anbessa specialized hospital, Addis Ababa Ethiopia, from January 01 to April 30, 2018: A prospective observational cohort study
| dc.contributor.advisor | Girma, Betelhem (Msc,Lecturer AAU.) | |
| dc.contributor.author | Gebeyehu, Geresu | |
| dc.date.accessioned | 2018-11-09T13:31:40Z | |
| dc.date.accessioned | 2023-11-05T09:40:03Z | |
| dc.date.available | 2018-11-09T13:31:40Z | |
| dc.date.available | 2023-11-05T09:40:03Z | |
| dc.date.issued | 2018-06 | |
| dc.description.abstract | Background: Post anesthesia shivering is one of the potential complications of anesthesia which may increase patient’s morbidity. Nowadays, it has become a common phenomenon with the increasing number of surgeries. Various pharmacological and non-pharmacological methods had been employed to control postoperative shivering. Warming the patient and other alternative methods has been employed over several years, but it was more expensive. Objectives: to compare the effectiveness of intravenous ketamine 0.5mg/kg and pethidine 0.5 mg/kg for post-operative shivering after general anesthesia at black lion specialized hospital from January 1 to April 30, 2018. Methods and materials: an observational cohort study was conducted at black lion specialized hospital from January 1 to April 30, 2018. The study involved 76 ASA I and II patients aged 18- 65 years, undergoing elective surgery under general anesthesia. The patients in the two groups took either ketamine 0.5mg/kg and pethidine 0.5 mg/kg 20 minutes before completion of the surgery. The incidence and severity of post-operative shivering were compared between the two groups every 10 minutes until one hour postoperatively. Categorical data were analyzed with the Chi-Square test and fisher exact test. Parametric data between groups were analyzed using independent samples t-test and non-parametric data were analyzed with Mann-Whitney U test. A p value of <0.05 was considered as a statistically significant. Results: The incidence of shivering between the ketamine and pethidine groups in PACU were (28.2%) and (35.9%) respectively (p=0.467). Grades of shivering were not significantly different between the two groups (p=0.893). Comparison of HR and MAP at different time intervals intraoperatively was found to be comparable between the groups (p>0.05). The scores of axillary temperature at different time intervals during intraoperative and postoperative period have shown comparable values. Conclusion and Recommendation: This study showed that prophylactic low dose IV ketamine reduced postoperative shivering as effectively as pethidine. The study also showed a clinically better outcome in favor of ketamine. We recommend prophylactic low dose IV ketamine 20 minutes before completion of surgery to prevent postoperative shivering. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/14086 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | ketamine, pethidine, general anesthesia, postoperative shivering, elective surgery | en_US |
| dc.title | Compare the Effectiveness of prophylactic intravenous ketamine 0.5mg/kg and pethidine 0.5mg/kg for postoperative shivering in patients undergoing elective surgery under general anesthesia at Tikur Anbessa specialized hospital, Addis Ababa Ethiopia, from January 01 to April 30, 2018: A prospective observational cohort study | en_US |
| dc.type | Thesis | en_US |