Assessment Of Quality of Life of Patients on long term diversion (Percutaneous Nephrostomy Versus Ureteral Stent) Cross-Sectional Comparative Study

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2025-12-01

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Addis Ababa University

Abstract

Background: Obstructive uropathy from Ureteral Obstruction often requires urinary diversion When Definitive treatment Cannot Be Performed Promptly or is not planned at all when patient is a terminal. Two Common Long-Term Diversion options are Percutaneous nephrostomy (PCN) and Ureteric Stenting (Double-J Stent). Understanding how These Modalities affect Patients’ quality of life (Qol) and Clinical Profile is Essential for Informed, Patient-Centered Decision-Making. This Study Attempted to Fill That Gap by Evaluating Qol and Patient Reported Symptoms in adults Managed with PCN versus Ureteric Stents for Prolonged Ureteral obstruction. Methods: This Cross-Sectional Comparative Study Was Conducted at AAU TASH Hospital. Eligible Participants Are Adults Who Have Undergone Urinary Diversion for Ureteral Obstruction and Have Maintained Their Device (PCN Or Ureteric Stent) for at least 90 days. Data Collection Includes Combined In-Person Interviews and Medical Records Review. Qol Was Assessed Using Validated Instruments (Including Euroqol EQ-5D-5L) and a Tube-Related Symptom Questionnaire. Demographic and Clinical were Recorded. Descriptive Statistics Was Used to Summarize Groups, And Inferential Analyses (E.G. Bivariate and Multivariable Regression) Were Used to Identify Factors Associated with Qol Differences Between PCN And Stent Groups, Controlling for Potential Confounders. Ethical Approval was Obtained, and Oral Informed Consent Was Secured from All Participants The PCN Group Mainly included patients with advanced malignancy while the stent group includes patient with benign diseases and prophylactic before major complication. Analysis showed the stent group had a significantly higher overall health state (VAS Mean 59.7 Vs. 43.0, P <0.001) and better overall quality of life in most dominas of euro ol 5D 5L : the Bivariate analysis Demonstrated that mode of diversion, Malignancy Status, Duration And Purpose of Diversion Were Both Highly Significant Predictors of Quality of Life (QOL), and The Subsequent Multiple Regression Confirmed That These only Mode of Diversion And Purpose of Diversion Factors Were The Strongest Independent Variables, Together Explaining 22.2% of The QOL Variance, while Other Clinical Variables Were Not Significant Conclusion-for long-Term Diversion in This Cohort, The Double-J Ureteral Stent is Associated with A Superior quality of life Compared to the Percutaneous nephrostomy. The External Nature of the PCN Tube Imposes an Overwhelming, Independent Burden on Patient Self-Care and Mobility. Clinical Decision-Making Must Prioritize Internal Drainage Whenever Clinically Feasible.

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Assessment Of Quality of Life of Patients on long, term diversion (Percutaneous Nephrostomy Versus Ureteral Stent), Cross-Sectional Comparative Study

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