Medication Adherence and Associated Factors Among Adult Heart Failure Patients at Selected Public Teaching Hospitals of Addis Ababa, Ethiopia, 2021.

No Thumbnail Available



Journal Title

Journal ISSN

Volume Title


Addis Ababa University


ABSTRACT Background: Heart failure is a progressive and complex clinical syndrome that can occur due to impairment of cardiac structure or function that leads to the inability of the heart to fill with or pump sufficient amount of blood to meet the metabolic need of the body. Medication adherence is crucial to controlling symptoms, delaying disease progression, and preventing hospitalization in heart failure. However, poor medication adherence is associated with increased re-hospitalization, morbidity, mortality and increased health care cost. Objective: This study aims to assess medication adherence and associated factors among adult heart failure patients at selected public health teaching hospitals in Addis Ababa, Ethiopia. Methods: A hospital based cross-sectional study among adult heart failure patients wasconducted at cardiac follow up clinic of Tikur anbessa specialized hospital, St. Paul’s millennium medical college, Armed force specialized Hospital and Yekatit 12 Hospital fromMarch 8-April 21,2021. A total of 385 patients were included and a systematic simple random sampling technique was used to select patients. Data collection was done through patient interview using pre tested structured questionnaire. The data was coded, edited, and entered in to Epi data version 4.4 then exported to SPSS version 25 for analysis. Variables having a p-value,0.25 in the bivariate analysis was a candidate for multivariable analysis. Variables having a p-value < 0.05 in the multivariable analysis were assumed as statistically significant factors. Results: A total of 385 participants were included with a response rate of 100%. More than half (67.8%) of the participants were females and the mean age was 46.27±16. Of the study participants (48.6%) adhered to medication. Education about medication AOR (95% CI) =2.127 (1.038,4.357), educational level AOR (95% CI) =6.044 (1.952,18.708) were positively associated with medication, fewer HF symptom AOR (95% CI) =0.044 (0.006,0.304), patient forgetfulness AOR (95% CI) =0.064 (0.034,0.121), cost of the drugs AOR (95% CI=0.413 (0.208,0.820) were negatively associated with medication adherence. Conclusion and recommendation: This study assessed the prevalence of medication adherence. The factors that affect medication adherence were education about medication, education level, fewer heart failure symptom, cost of medication and patient forgetfulness. Health professionals should give education about medication to improve treatment adherence.



Heart failure, medication adherence, Hospitals, Addis Ababa, Ethiopia