Assessment of Quality of Life among Children with Epilepsy and Associated Factors in Governmental Hospitals of Addis Ababa, Ethiopia,2021.
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Date
2022
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Addis Ababa University
Abstract
Abstract
Background: Quality of life (QOL) is increasingly recognized as an important patient-reported
outcome in health care research. However, the use is still restricted. Epilepsy impact was far
more frequently evaluated considering QOL but only focused on adult patients so this research
focused on children.
Objective: To assess the quality of life among children between (7-18) with epilepsy and
associated factors in governmental Hospitals in Addis Ababa, Ethiopia 2021.
Methods: A facility-based cross-sectional study design was employed and data was collected
from 564 children using a face-to-face interview in Addis Ababa from November 2020 to
January 2021 selected using multi-stage sampling method. Probability proportionate to size
technique was applied to select children from each hospital. The data was cleaned, entered
through EPI-INFO 3.1and exported to STATA version 15.0 for analysis. Frequency distributions
of variables were tabulated. The raw numbers of the five-point Likert scale for QOLIE-CH-48
domain scores were converted into a 0-100-point response scale, with higher scores indicating
better QOL.ANOVA was used to assess the relationship between quality of life and the
independent variables. Multiple linear regression was conducted to identify factors predicting
quality of life. The threshold for statistical significance was p<0.05.
Result: -A total of 564 children participated with a response rate of 94.1%. The mean score of
quality of life was 60.18±8.68 (95% CI: 59.05, 61.23). Self-depression (P= 0.0094 F=3.39),
number of anti-epileptic drug (AED) (P=0.0021 F=4.97), types of seizure (P= 0.000, F=52.26)
were statistically significant predictors of QOL.A score in quality of life increased by 5.03 for
every unit increase in a score of seizure frequency per week with (β= 5.0395% CI:0.4 -
0.9).Quality of life of epileptic patients increased by 0.19 and 1.99 in every unit increase in a
score of stigma and anxiety (β= 0.1995% CI: (-0.1 - 0.1) and(β=1.99, 95%CI: 0.007- 1.03)
respectively.
Conclusion: -The quality of life among children with epilepsy was low. Stigma, seizure,
depression and anxiety, and AED side effects were statically significant for quality of life.
Implementing interventions that focus on early detection like self depression and stigma in
children with epilepsy should be of great concern for healthcare providers.
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Keywords
Epilepsy, quality of life, children, Addis Ababa, hospitals