Effect of Low Dose Intrathecal Pethidine (0.2mg/Kg) Added to Bupivacaine on Prevention Intraoperative Shivering Among Geriatric Patients Undergoing Elective Surgery Under Spinal Anesthesia an Institution Based Prospective Cohort Study 2022/23
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Date
2023-05-30
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Addis Ababa University
Abstract
Shivering is one of the most common unpleasant problems associated with spinal anesthesia, causing dissatisfaction and undesirable complications in patients undergoing elective surgery under spinal anesthesia. However, the prevention of shivering has not been thoroughly investigated. This study aims to assess the effect of low-dose intrathecal pethidine on the prevention of intraoperative shivering among geriatric patients undergoing elective surgery under spinal anesthesia.
Objective : The objective of this study is to compare the effect of low-dose intrathecal pethidine (0.2mg/kg) added to bupivacaine and bupivacaine alone on the prevention of intraoperative shivering among geriatric patients undergoing elective surgery under spinal anesthesia at St Peter Specialized Hospital from January 1/23 to April 30/23.
Methods: A Prospective cohort study was conducted. The study participants were allocated into two groups: those given low-dose (0.2mg/kg) intrathecal pethidine with bupivacaine and those given bupivacaine alone, based on the medication administered by the responsible anesthetist. The data were analyzed using student’s t-test or Mann–Whitney U test, based on the normality of distribution, and the results were presented as mean ± SD. The categorical data were analyzed using the chi-square test, and the results were presented as frequency and percentage. A p-value of less than 0.05 was considered statistically significant.
Results: The incidence of shivering was observed to be 72.4% in the non-exposed group and 24.14% in the exposed group, which is statistically significant with a p-value <0.05 (0.0000…). Additionally, there was a stastiscally significant difference the intensity of shivering between the two groups, with p- value of <0.05 (0.003).
Conclusion: Administering a low dose (0.2mg/kg) of intrathecal pethidine with bupivacaine is effective in reducing the incidence and intensity of intraoperative shivering among geriatric patients undergoing elective surgery under spinal anesthesia, although it may cause mild pruritus.