Sociodemographic features, Clinical characteristics and Treatment patterns of inflammatory bowel disease in patients seen at Tikur Anbessa Specialized Hospital (TASH) during the period between January - August 2020, Addis Ababa, Ethiopia.

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Addis Abeba University


Background: Inflammatory bowel diseases (IBD) include ulcerative colitis (UC) and Crohn’s disease (CD). To date there are no reports from Ethiopia at a nationwide or hospital levels about the epidemiology and clinical characteristics of IBD. Objective: To describe the sociodemographic features, clinical characteristics and treatment patterns of IBD in our patients. Methods and Materials: A descriptive study consisted of 102 patients who attended the GI referral clinic in TASH from January - August 2020. Data was gathered through review of medical records and patient interview; and a standardized questionnaire was applied. The collected data was analyzed using SPSS v. 26. Results: A total of 102 IBD patients (29 UC, 73 CD and a ratio of 2.5:1) with female predominance, 57% (n = 58) was identified. The M-to-F ratio was 1:1.2 for CD and 1:1.6 for UC. The mean age at diagnosis was 26.4 years for CD and 33 years for UC. Only 5.9% of patients had a family history of IBD; and no association of smoking with IBD was found. EIMs were reported in 16.6%. In patients with CD, the ileo-colon type was the most common disease phenotype (38%), and the inflammatory type was the most common disease behavior (49.3%); 18.6% ended up in bowel resection. In patients with UC, left-sided colitis was the predominant disease extent (69.0%). Majority of the patients were on steroids and immunomodulators. Conclusions: There was a predominance of females in both IBD subtypes. CD was more common than UC, in comparison to what is mentioned in most literatures and the mean age at diagnosis was in the mid-twenties for the former and early thirties for the later. None of the IBD patients were treated with biologic therapy.



IBD, Crohn’s disease, Ulcerative colitis, demography, clinical pattern, TASH,Ethiopia