Assessment of Statin Utilization Pattern for Primary Prevention in Patients with Type 2 DM Who have Follow up at Diabetic Clinic in Tikur Anbessa Specialized Hospital; A Hospital-Based Cross Sectional Study, 2021
No Thumbnail Available
Date
2021-12
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Addis Abeba University
Abstract
Background: cardiovascular disease is the leading cause of morbidity and mortality among type
2 diabetic (T2DM) patients. Statin therapy is effective in reducing cardiovascular events for both
primary and secondary prevention of ASCVD.
Objective: to assess statin utilization extent for primary prevention of CVD in patients with type
2 DM who are above 40yrs having follow up at diabetic clinic TASH.
Methods and materials: a hospital based cross-sectional study was conducted based on data
collected using structured questionnaire by face-to-face interview and the digital record system
from june 10, 2021, to September 20,2021.Data entry was made using Epi info version 3.1 and
was analyzed using SPSS software version 25.
RESULT: A total of 376 of patients with the age above of 40 with T2DM were participated in
this study. statin prescription rate was 87.4%. almost all of patients (99.1%) who are taking
statin were on moderate intensity and above with 59.3%% and 39.8%% received moderate and
high -intensity statin respectively. From the study conducted, the most commonly prescribed
statin was Atorvastatin (85.6%). Predictors of statin prescription were age, use of Both insulin
and metformin, occupational status and monthly income as independent determinants of statin
use. Use of both insulin and metformin increased the odds of statin use by 2.29 times as
compared to the counterparts [AOR= 2.29; 95% CI: 1.07, 4.95]. Having other occupation led to
79% less odds for statin use as compared to government employees [AOR=0.21; 95% CI: 0.09,
0.51]. For each 1-year increase in the age of the patients, the odds of using statin increases by 5%
[AOR= 1.05; 95% CI: 1.02, 1.10].
CONCLUSION: In conclusion this study done at showed the highest rate of statin prescription
of 87% for primary prevention of ASCVD in type 2 DM patients who are above 40 compared to
other studies done recently.Which is consistent with contemporary guidelines recommendation
for dyslipidemia and primary prevention of ASCVD.
Description
Keywords
Type 2 DM, Statins, Utilization Pattern, Addis Ababa