Prevalence of Asymptomatic Microscopic Hematuria in 7-12 Years School Age Children of Medhanealem Primary School in Addis Ababa
| dc.contributor.advisor | Shimelis Damte | |
| dc.contributor.author | Yeshidinber Abate | |
| dc.date.accessioned | 2018-06-12T09:08:26Z | |
| dc.date.accessioned | 2023-11-05T09:33:51Z | |
| dc.date.available | 2018-06-12T09:08:26Z | |
| dc.date.available | 2023-11-05T09:33:51Z | |
| dc.date.issued | 2014-10 | |
| dc.description.abstract | Background:Hematuria is one of the most important signs of renal or bladder disease in children and itcan represent a process that is simple and benign or complex and life threatening.Asymptomatic microscopic hematuria is common in unselected populations of children, witha prevalence that ranges from 0.4% to 4.1% depending on the criteria used to definehematuria.Urine analysis, a simple and inexpensive test, is the cornerstone in the evaluation of thekidney function. Proteinuria or hematuria may be the only early signs of renal diseaseincluding membranous nephropathy, membranoproliferative glomerulonephritis, postinfectious glomerulonephritis, IgA nephropathy and others. The basic dipstick method is themost rapid screening procedure that could be helpful in the early detection of renal or urinarytract diseases among apparently healthy or asymptomatic subjects in the hope of preventingand retarding progression to chronic renal failure. Many countries have used this screeningprogram to prevent and follow children with asymptomatic children. However the prevalenceof asymptomatic hematuria is unknown in Ethiopia and there is no recommendation onroutine screening urinalysis in Ethiopian school children. Objective:To determine the prevalence of asymptomatic hematuria in school age children inAddis Ababa Methods:A cross sectional survey using urinalysis was done over a period of 8 weeks in 382 apparentlyhealthy school age children (7-12 years) at MAPS in Addis Ababa. The children who testedpositive in the first screening were re-tested after 2 weeks. Results:In the first screening 32 children (8.4 %) tested positive for hematuria. Of these children, 16(4.2 %) cases tested positive in a second screening. The prevalence was both age and sexdependent. Co-existing proteinuria and leucocytes were common findings (19.6 % and 8.4 %respectively) where as pyuria, glycosuria and nitrite were seen in < 1% of children. Glomerulonephritis was the most commonly detected disorder (43.75%). 75 students (19.6%)were positive for protein,7 students(1.8%) were positive for both blood and protein, 1student(0.3%) was positive for glucose,1 student (0.3%) was positive for nitrite ,32 students(8.4%) were positive for leukocyte- esterase.88Subsequently, 10 children from the secondary screening group were lost to follow up andonly 6 students were referred to TAH pediatric renal clinic. Conclusions:This study helped to assess the prevalence of urinary abnormalities in school-aged childrenfor the first time in Ethiopia. Urine abnormalities are common finding among apparentlyhealthy school aged children with hematuria and proteinuria being the most prevailingabnormalities. Our study demonstrated that hematuria is higher in Ethiopian children thanother African children and worldwide. Coexisting urinary abnormalities especiallyLeukocyturia and proteinuria (most are trace) are common while nitrituria and glucosuria areuncommon. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/463 | |
| dc.language.iso | en | en_US |
| dc.subject | Asymptomatic microscopic hematuria;Proteinuria | en_US |
| dc.title | Prevalence of Asymptomatic Microscopic Hematuria in 7-12 Years School Age Children of Medhanealem Primary School in Addis Ababa | en_US |
| dc.type | Thesis | en_US |