A comparative study on effect of tracheal tube cuffsfilled with air versus alkalinized lidocaine on hemodynamic response changes during extubation and postoperative laryngotrachial morbidities in childrens.
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Date
2020-06
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Addis Abeba University
Abstract
INTRODUCTION: When the lateral pressure exerted by an inflated cuff on tracheal mucosa
exceeds capillary perfusion pressure, it can result in tracheal morbidity, loss of mucosal cilia,
ulceration, hemorrhage, and tracheal stenosis. Patients may complain of cough, sore throat and
hoarseness in the postoperative period. Lidocaine within tracheal tube cuffs seems to exert a
localized effect on the trachea after diffusing through the cuff, resulting in improved tolerance to
tracheal. Both alkalinized and non-alkalinized lidocaine used to fill tracheal tube cuffs reduces
the incidence of postoperative sore throat.
OBJECTIVE: was to assess the effectiveness of tracheal tube cuffs filled with air verses
alkalinized lidocaine on heamodynamic response changes and laryngotracheal tracheal
morbidities during and post extubation in children’s.
METHODOLOGY: Institutional based observational prospective cohort study design used to
address the study objective. All elective children aged 3-13 years who undergoing operation
under general anesthesia with endotracheal intubation greater than one hour at TASH were
selected. The outcome variable ware Haemodynamic response changes i.e. (HR,SBP and DBP),
was measured in the 5 min before, and 5 min following, tracheal extubation and laryngotracheal
morbidities like cough, hoarsens and sore throat, evaluated as dichotomous variables (yes or no).
RESULTS: Hemodynamic changes that recorded during the study were the highest systolic and
diastolic blood pressure and the heart rate. The results shows the heat rate difference of p value
<0.001. Meanwhile the systolic blood pressures 8 hour after extubation between the groups were
with p value of 0.003. The incidence of sore throat post operatively measured at 8hr has a
significantly lowered in alkalinized lidocaine groups compared to air with p value difference of
0.027.Meanwhile the incidence of postoperative sore throat that is measured at 24 hour shows
significant difference among the groups with p value of 0.009.
CONCLUSION: Alkalinized lidocaine inflated tracheal tubes have shows improved
hemodynamic and larngotracheal morbidities in children’s.
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Keywords
Tracheal tube,alkalinized lidocaine,extubation , postoperative